PMID- 18449991 OWN - NLM STAT- MEDLINE DCOM- 20080605 LR - 20080502 IS - 1064-3745 (Print) IS - 1064-3745 (Linking) VI - 409 DP - 2007 TI - The IMGT/HLA database. PG - 43-60 LID - 10.1007/978-1-60327-118-9_3 [doi] AB - The human leukocyte antigen (HLA) complex is located within the 6p21.3 region on the short arm of human chromosome 6 and contains more than 220 genes of diverse function. Many of the genes encode proteins of the immune system and include many highly polymorphic HLA genes. The naming of new HLA genes and allele sequences and their quality control is the responsibility of the WHO Nomenclature Committee for Factors of the HLA System. The IMGT/HLA Database acts as the repository for these sequences and is recognized as the primary source of up-to-date and accurate HLA sequences. The IMGT/HLA website provides a number of tools for accessing the database: these include allele reports, sequence alignments, and sequence similarity searches. The website is updated every 3 months with all the new and confirmatory sequences submitted to the WHO Nomenclature Committee. Submission of HLA sequences to the committee is possible through the tools provided by the IMGT/HLA Database. FAU - Robinson, James AU - Robinson J AD - Anthony Nolan Research Institute, Royal Free Hospital, Hampstead, London, UK. FAU - Marsh, Steven G E AU - Marsh SG LA - eng GR - Cancer Research UK/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Methods Mol Biol JT - Methods in molecular biology (Clifton, N.J.) JID - 9214969 RN - 0 (HLA Antigens) SB - IM MH - Alleles MH - Computational Biology MH - *Databases, Genetic MH - Genes, MHC Class I MH - Genes, MHC Class II MH - HLA Antigens/classification/*genetics MH - Humans MH - Immunogenetics/*statistics & numerical data MH - Internet MH - Sequence Alignment/statistics & numerical data MH - Terminology as Topic MH - User-Computer Interface EDAT- 2008/05/03 09:00 MHDA- 2008/06/06 09:00 CRDT- 2008/05/03 09:00 PHST- 2008/05/03 09:00 [pubmed] PHST- 2008/06/06 09:00 [medline] PHST- 2008/05/03 09:00 [entrez] AID - 10.1007/978-1-60327-118-9_3 [doi] PST - ppublish SO - Methods Mol Biol. 2007;409:43-60. doi: 10.1007/978-1-60327-118-9_3.