PMID- 18449998
OWN - NLM
STAT- MEDLINE
DCOM- 20080605
LR  - 20080502
IS  - 1064-3745 (Print)
IS  - 1064-3745 (Linking)
VI  - 409
DP  - 2007
TI  - Structural basis for HLA-A2 supertypes.
PG  - 155-62
LID - 10.1007/978-1-60327-118-9_10 [doi]
AB  - The human leukocyte antigen (HLA) alleles are extremely polymorphic among ethnic 
      population, and the peptide-binding specificity varies for different alleles in a 
      combinatorial manner. However, it has been suggested that majority of alleles can 
      be covered within few HLA supertypes, where different members of a supertype bind 
      similar peptides, yet exhibiting distinct repertoires. Nonetheless, the 
      structural basis for HLA supertype-like function is not clearly known. Here, we 
      use structural data to explain the molecular basis for HLA-A2 supertypes.
FAU - Kangueane, Pandjassarame
AU  - Kangueane P
AD  - School of Mechanical and Aerospace Engineering, Nanyang Technological University, 
      Singapore.
FAU - Sakharkar, Meena Kishore
AU  - Sakharkar MK
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Methods Mol Biol
JT  - Methods in molecular biology (Clifton, N.J.)
JID - 9214969
RN  - 0 (HLA-A2 Antigen)
SB  - IM
MH  - Alleles
MH  - Amino Acid Sequence
MH  - Binding Sites/genetics
MH  - Computational Biology
MH  - Genes, MHC Class I
MH  - HLA-A2 Antigen/*chemistry/*classification/genetics
MH  - Humans
MH  - Immunogenetics
EDAT- 2008/05/03 09:00
MHDA- 2008/06/06 09:00
CRDT- 2008/05/03 09:00
PHST- 2008/05/03 09:00 [pubmed]
PHST- 2008/06/06 09:00 [medline]
PHST- 2008/05/03 09:00 [entrez]
AID - 10.1007/978-1-60327-118-9_10 [doi]
PST - ppublish
SO  - Methods Mol Biol. 2007;409:155-62. doi: 10.1007/978-1-60327-118-9_10.