PMID- 1845002
OWN - NLM
STAT- MEDLINE
DCOM- 19930617
LR  - 20191028
IS  - 1050-1606 (Print)
IS  - 1050-1606 (Linking)
VI  - 1
IP  - 3
DP  - 1991 Sep
TI  - Plasma glucose kinetics in a well-trained cyclist fed glucose throughout 
      exercise.
PG  - 279-88
AB  - We hypothesized that when plasma glucose availability is maintained by 
      carbohydrate (CHO) ingestion, trained cyclists can utilize plasma glucose at very 
      high rates during the later stages of prolonged exercise (10). To test this 
      hypothesis, a well-trained male cyclist was studied during exercise to fatigue at 
      70% VO2max when ingesting glucose throughout exercise. A primed continuous 
      infusion of [U-13C]glucose was begun after 60 min of exercise to measure rates of 
      plasma glucose appearance (Ra), disappearance (Rd), and oxidation (R(ox)). Ra and 
      Rd rose progressively throughout exercise, peaking at 6.85 and 6.99 mmol/min, 
      respectively, at fatigue (i.e., 133 min). Most (93%) of this glucose was 
      oxidized; during the final 30 min of exercise, R(ox) averaged 6.10 mmol/min and 
      accounted for approximately half of total CHO oxidation. These results support 
      the hypothesis that trained cyclists can oxidize plasma glucose at very high 
      rates during the later stages of prolonged exercise when fed CHO.
FAU - Coggan, A R
AU  - Coggan AR
AD  - Exercise Physiology Laboratory, Ohio State University, Columbus 43210.
FAU - Spina, R J
AU  - Spina RJ
FAU - Kohrt, W M
AU  - Kohrt WM
FAU - Bier, D M
AU  - Bier DM
FAU - Holloszy, J O
AU  - Holloszy JO
LA  - eng
GR  - AG-00078/AG/NIA NIH HHS/United States
GR  - AM-20579/AM/NIADDK NIH HHS/United States
GR  - RR-00954/RR/NCRR NIH HHS/United States
GR  - etc.
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Int J Sport Nutr
JT  - International journal of sport nutrition
JID - 9307702
RN  - 0 (Blood Glucose)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Lactates)
RN  - 33X04XA5AT (Lactic Acid)
RN  - IY9XDZ35W2 (Glucose)
RN  - PDC6A3C0OX (Glycerol)
SB  - IM
MH  - Adult
MH  - Bicycling/*physiology
MH  - Blood Glucose/*metabolism
MH  - Fatty Acids, Nonesterified/blood
MH  - Glucose/*administration & dosage
MH  - Glycerol/blood
MH  - Humans
MH  - Infusions, Intravenous
MH  - Kinetics
MH  - Lactates/blood
MH  - Lactic Acid
MH  - Male
MH  - Oxidation-Reduction
MH  - Perception/physiology
MH  - Pulmonary Gas Exchange
EDAT- 1991/09/01 00:00
MHDA- 1991/09/01 00:01
CRDT- 1991/09/01 00:00
PHST- 1991/09/01 00:00 [pubmed]
PHST- 1991/09/01 00:01 [medline]
PHST- 1991/09/01 00:00 [entrez]
AID - 10.1123/ijsn.1.3.279 [doi]
PST - ppublish
SO  - Int J Sport Nutr. 1991 Sep;1(3):279-88. doi: 10.1123/ijsn.1.3.279.