PMID- 18454301 OWN - NLM STAT- MEDLINE DCOM- 20081023 LR - 20240213 IS - 1873-4626 (Electronic) IS - 1091-255X (Linking) VI - 12 IP - 7 DP - 2008 Jul TI - Responsiveness and minimal clinically important differences after cholecystectomy: GIQLI versus SF-36. PG - 1275-82 LID - 10.1007/s11605-008-0526-7 [doi] AB - INTRODUCTION: To compare responsiveness and minimal clinically important differences (MCID) between the Gastrointestinal Quality of Life (GIQLI) and the Short Form 36 (SF-36), we prospectively analyze 159 patients undergoing cholecystectomy at two tertiary academic hospitals. PATIENTS AND METHODS: All patients completed the disease-specific GIQLI and the generic SF-36 before and 3 months after surgery. Scores using these instruments were interpreted by generalized estimating equation before and after cholecystectomy. The bootstrap estimation was used to derive 95% confidence intervals for differences in the responsiveness estimates. RESULTS AND DISCUSSION: Mean changes in all GIQLI and the SF-36 subscales were statistically significant (p < 0.05). Comparisons of effect size (ES), standardized response means (SRM), and relative efficiency (>1) indicated that the responsiveness of the GIQLI was superior to that of the SF-36. In the equivalence test, all lower or upper confidence limits presented no equivalence (>5), indicating good MCID. The ES and SRM for emotions and physical function in the GIQLI significantly differed from those of the SF-36 (p < 0.05). CONCLUSION: The data in this study indicate that clinicians and health researchers should weight disease-specific measures more heavily than generic measures when evaluating treatment outcomes. FAU - Shi, Hon-Yi AU - Shi HY AD - Graduate Institute of Healthcare Administration, Kaohsiung Medical University, 100-Shih-Chun 1st Road, Kaohsiung, Taiwan. FAU - Lee, Hao-Hsien AU - Lee HH FAU - Chiu, Chong-Chi AU - Chiu CC FAU - Chiu, Herng-Chia AU - Chiu HC FAU - Uen, Yih-Huei AU - Uen YH FAU - Lee, King-Teh AU - Lee KT LA - eng PT - Comparative Study PT - Journal Article PT - Multicenter Study DEP - 20080503 PL - Netherlands TA - J Gastrointest Surg JT - Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract JID - 9706084 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Cholecystectomy/*methods MH - Female MH - Follow-Up Studies MH - *Health Status Indicators MH - Humans MH - Male MH - Middle Aged MH - Patient Satisfaction MH - Postoperative Period MH - *Quality of Life MH - *Surveys and Questionnaires MH - Taiwan MH - Treatment Outcome EDAT- 2008/05/06 09:00 MHDA- 2008/10/24 09:00 CRDT- 2008/05/06 09:00 PHST- 2008/01/30 00:00 [received] PHST- 2008/03/26 00:00 [accepted] PHST- 2008/05/06 09:00 [pubmed] PHST- 2008/10/24 09:00 [medline] PHST- 2008/05/06 09:00 [entrez] AID - S1091-255X(23)08748-6 [pii] AID - 10.1007/s11605-008-0526-7 [doi] PST - ppublish SO - J Gastrointest Surg. 2008 Jul;12(7):1275-82. doi: 10.1007/s11605-008-0526-7. Epub 2008 May 3.