PMID- 18475125
OWN - NLM
STAT- MEDLINE
DCOM- 20080926
LR  - 20090528
IS  - 1558-2027 (Print)
IS  - 1558-2027 (Linking)
VI  - 9
IP  - 6
DP  - 2008 Jun
TI  - Weight loss and quality of life in chronic heart failure patients.
PG  - 576-80
LID - 10.2459/JCM.0b013e3282f2de13 [doi]
AB  - OBJECTIVES: To evaluate the impact of a planned body weight reduction on quality 
      of life (QoL) in obese/overweight chronic heart failure (CHF) patients. METHODS: 
      Thirty-four obese/overweight chronic heart failure patients (24 men, mean age 
      67.8 +/- 9.4 years) underwent a 6-month dietary programme. An assessment of 
      clinical and biochemical parameters was executed before and after dietary 
      programme. The QoL was judged by means of the Kansas City Cardiomyopathy 
      Questionnaire (KCCQ) at baseline and at the end of the programme. RESULTS: 
      End-study BMI (P < 0.005) and body weight (P < 0.04) values were significantly 
      reduced. We observed a significant improvement in the mean New York Heart 
      Association (NYHA) functional class value (P < 0.02) and in the left ventricle 
      ejection fraction (LVEF) (P < 0.05). The end-study KCCQ scores were significantly 
      increased in seven out of eight domains. We identified a cut-off value of body 
      weight loss of 3 kg to separate responder patients from the nonresponder ones. 
      Only responder group patients showed a significant variation in BMI (P < 0.04), 
      body weight (P < 0.03), mean NYHA class value (P < 0.05), LVEF (P < 0.05). 
      Moreover, all KCCQ domain scores significantly increased in the responder group 
      only. CONCLUSION: A diet-based body weight reduction improved the quality of life 
      and, perhaps, the cardiac function. Benefits are already evident with a small 
      reduction in body weight.
FAU - Mariotti, Rita
AU  - Mariotti R
AD  - Division of Cardiology, Cardiac and Thoracic Department, University of Pisa, 
      Pisa, Italy.
FAU - Castrogiovanni, Francesca
AU  - Castrogiovanni F
FAU - Canale, Maria Laura
AU  - Canale ML
FAU - Borelli, Gabriele
AU  - Borelli G
FAU - Rondinini, Lorenzo
AU  - Rondinini L
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cardiovasc Med (Hagerstown)
JT  - Journal of cardiovascular medicine (Hagerstown, Md.)
JID - 101259752
SB  - IM
MH  - Aged
MH  - Chronic Disease
MH  - *Diet, Reducing
MH  - Female
MH  - Heart Failure/complications/*diet therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Obesity/complications/*diet therapy
MH  - *Quality of Life
MH  - *Weight Loss
EDAT- 2008/05/14 09:00
MHDA- 2008/09/27 09:00
CRDT- 2008/05/14 09:00
PHST- 2008/05/14 09:00 [pubmed]
PHST- 2008/09/27 09:00 [medline]
PHST- 2008/05/14 09:00 [entrez]
AID - 01244665-200806000-00005 [pii]
AID - 10.2459/JCM.0b013e3282f2de13 [doi]
PST - ppublish
SO  - J Cardiovasc Med (Hagerstown). 2008 Jun;9(6):576-80. doi: 
      10.2459/JCM.0b013e3282f2de13.