PMID- 18480657 OWN - NLM STAT- MEDLINE DCOM- 20080624 LR - 20080523 IS - 0002-9629 (Print) IS - 0002-9629 (Linking) VI - 335 IP - 5 DP - 2008 May TI - Acute peritonitis as presentations of tuberculosis-associated immune reconstitution inflammatory syndrome in an HIV-infected man. PG - 387-9 LID - 10.1097/MAJ.0b013e318149e6de [doi] AB - Immune reconstitution inflammatory syndrome (IRIS) is particularly observed after the start of therapy for pathogenic antigens in patients infected with human immunodeficiency virus (HIV) and receiving highly active antiretroviral therapy (HAART). Although tuberculosis (TB)-associated IRIS is the most common form, its presentation as a primary feature of acute peritonitis is extraordinarily rare. We report a 43-year-old man diagnosed with acquired immunodeficiency syndrome and pulmonary TB coinfection. His symptoms, sputum quantity, and chest radiologic appearance improved markedly after 3 weeks of antituberculous therapy, and HAART was initiated on the fourth week. However, acute abdomen with peritoneal signs resulting from the established tuberculous peritonitis developed on the seventh day of HAART. His clinical symptoms resolved after maintenance of HAART and antituberculous regimens. Tuberculous peritonitis must be considered in the differential diagnosis of acute abdomen in HIV-infected patients on antiviral therapy, especially in patients with known underlying TB. Early recognition of IRIS is important when managing HIV-infected patients with opportunistic infections. FAU - Wu, Shih-Wei AU - Wu SW AD - Division of Pulmonary and Critical Care Medicine, Department of Medicine, Division of Infectious Diseases and Tropical Medicine, Tri-Service General Hospital, Taipei, Taiwan, Republic of China. FAU - Chen, Cheng-Jueng AU - Chen CJ FAU - Lin, Te-Yu AU - Lin TY FAU - Wang, Ning-Chi AU - Wang NC LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Am J Med Sci JT - The American journal of the medical sciences JID - 0370506 SB - IM MH - AIDS-Related Opportunistic Infections/*complications/immunology MH - Acute Disease MH - Adult MH - Antiretroviral Therapy, Highly Active/*adverse effects MH - HIV Infections/drug therapy MH - Humans MH - Male MH - Peritonitis/*etiology MH - Systemic Inflammatory Response Syndrome/*etiology MH - Tuberculosis/*complications/immunology EDAT- 2008/05/16 09:00 MHDA- 2008/06/25 09:00 CRDT- 2008/05/16 09:00 PHST- 2008/05/16 09:00 [pubmed] PHST- 2008/06/25 09:00 [medline] PHST- 2008/05/16 09:00 [entrez] AID - S0002-9629(15)32307-7 [pii] AID - 10.1097/MAJ.0b013e318149e6de [doi] PST - ppublish SO - Am J Med Sci. 2008 May;335(5):387-9. doi: 10.1097/MAJ.0b013e318149e6de.