PMID- 18482082
OWN - NLM
STAT- MEDLINE
DCOM- 20090601
LR  - 20151119
IS  - 1399-3038 (Electronic)
IS  - 0905-6157 (Linking)
VI  - 19
IP  - 4
DP  - 2008 Jun
TI  - Peanut and tree nut allergy in childhood.
PG  - 368-73
LID - 10.1111/j.1399-3038.2008.00723.x [doi]
AB  - Peanut and tree nut allergies present multiple challenges in their presentation 
      and management. These challenges have become increasingly relevant in recent 
      years, as these allergies appear to have become more common. An estimated 1-2% of 
      the population in the USA is allergic to peanut or tree nuts. Peanut allergy 
      typically presents with symptoms in one of the first few exposures to peanut. 
      Diagnosis is based on clinical history along with skin prick test, or 
      quantitation of allergen-specific immunoglobulin E (IgE), and oral food 
      challenges when indicated. Once the diagnosis is confirmed, the only current 
      management approach is strict avoidance of the food. This is clearly an imperfect 
      option as it can be difficult to avoid completely peanut and tree nuts and 
      accidental exposures are not uncommon. Only about 20% of those with peanut 
      allergy, and <10% of those with tree nut allergy, are reported to acquire 
      tolerance. Additionally, peanut allergy can recur, with one study finding a 
      recurrence rate of 8%. Peanut and tree nuts are the foods most frequently 
      associated with fatal episodes of anaphylaxis. This is of particular concern in 
      adolescents and young adults, among whom life-threatening and fatal food 
      allergy-related reactions are most common.
FAU - Skripak, Justin M
AU  - Skripak JM
AD  - Division of Allergy and Immunology, The Johns Hopkins University School of 
      Medicine, Baltimore, MD 21287, USA.
FAU - Wood, Robert A
AU  - Wood RA
LA  - eng
GR  - 5T32 AI07007/AI/NIAID NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Pediatr Allergy Immunol
JT  - Pediatric allergy and immunology : official publication of the European Society 
      of Pediatric Allergy and Immunology
JID - 9106718
RN  - 0 (Anti-Allergic Agents)
RN  - 8GTS82S83M (Diphenhydramine)
RN  - QF8SVZ843E (Albuterol)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
MH  - Adolescent
MH  - Albuterol/therapeutic use
MH  - Anti-Allergic Agents/therapeutic use
MH  - Arachis
MH  - Child, Preschool
MH  - Diphenhydramine/therapeutic use
MH  - Epinephrine/therapeutic use
MH  - Female
MH  - Humans
MH  - Male
MH  - Nut Hypersensitivity/diagnosis/*drug therapy/*physiopathology
MH  - Patient Education as Topic
MH  - Peanut Hypersensitivity/diagnosis/*drug therapy/*physiopathology
MH  - Radioallergosorbent Test
MH  - Skin Tests
EDAT- 2008/05/17 09:00
MHDA- 2009/06/02 09:00
CRDT- 2008/05/17 09:00
PHST- 2008/05/17 09:00 [pubmed]
PHST- 2009/06/02 09:00 [medline]
PHST- 2008/05/17 09:00 [entrez]
AID - PAI723 [pii]
AID - 10.1111/j.1399-3038.2008.00723.x [doi]
PST - ppublish
SO  - Pediatr Allergy Immunol. 2008 Jun;19(4):368-73. doi: 
      10.1111/j.1399-3038.2008.00723.x.