PMID- 18483997
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20080516
IS  - 0307-9457 (Print)
IS  - 0307-9457 (Linking)
VI  - 27
IP  - 3
DP  - 1998
TI  - Some strains of serotype 4 fowl adenoviruses cause inclusion body hepatitis and 
      hydropericardium syndrome in chickens.
PG  - 269-76
LID - 10.1080/03079459808419335 [doi]
AB  - Fowl adenoviruses were isolated and characterized from severe cases of 
      hydropericardium syndrome in Ecuador and Pakistan. All were neutralized by 
      antibodies against serotypes 4 and 11. Cross-neutralization tests and restriction 
      enzyme analysis strengthen the classification as serotype 4 strains. The 
      restriction endonucleases used allowed the differentiation among field isolates 
      and reference strains. All field isolates tested induced high embryo mortality. 
      One-day-old specific pathogen free (SPF) chicks were infected with 10(5) 
      plaque-forming units by natural routes to reproduce the disease with plaque 
      purified virus. Whereas no mortality was seen with the reference strain, the 
      mortality with the field isolates was 100%. A reduced mortality occurred with a 
      lower infectious dose. Field isolate K1013 from Ecuador was also highly 
      pathogenic for 1- to 3-week-old SPF chicks after intramuscular inoculation. The 
      main pathological signs were swollen livers, severe hydropericardium and 
      nephritis, reflecting the field situation and underlining the role of FAV4 
      strains in the aetiology of infectious hydropericardium.
FAU - Mazaheri, A
AU  - Mazaheri A
AD  - Institut fur Geflugelkrankheiten, Freie Universitut Berlin, Berlin, Germany.
FAU - Prusas, C
AU  - Prusas C
FAU - Voss, M
AU  - Voss M
FAU - Hess, M
AU  - Hess M
LA  - eng
PT  - Journal Article
PL  - England
TA  - Avian Pathol
JT  - Avian pathology : journal of the W.V.P.A
JID - 8210638
EDAT- 2008/05/17 09:00
MHDA- 2008/05/17 09:01
CRDT- 2008/05/17 09:00
PHST- 2008/05/17 09:00 [pubmed]
PHST- 2008/05/17 09:01 [medline]
PHST- 2008/05/17 09:00 [entrez]
AID - 784670354 [pii]
AID - 10.1080/03079459808419335 [doi]
PST - ppublish
SO  - Avian Pathol. 1998;27(3):269-76. doi: 10.1080/03079459808419335.