PMID- 18488869
OWN - NLM
STAT- MEDLINE
DCOM- 20080811
LR  - 20080520
IS  - 0017-7768 (Print)
IS  - 0017-7768 (Linking)
VI  - 147
IP  - 3
DP  - 2008 Mar
TI  - [Physical activity: positive impact on brain plasticity].
PG  - 252-5, 276
AB  - The central nervous system has a unique capability of plasticity that enables a 
      single neuron or a group of neurons to undergo functional and constructional 
      changes that are important to learning processes and for compensation of brain 
      damage. The current review aims to summarize recent data related to the effects 
      of physical activity on brain plasticity. In the last decade it was reported that 
      physical activity can affect and manipulate neuronal connections, synaptic 
      activity and adaptation to new neuronal environment following brain injury. One 
      of the most significant neurotrophic factors that is critical for synaptic 
      re-organization and is influenced by physical activity is brain-derived 
      neurotrophic factor (BDNF). The frequency of physical activity and the intensity 
      of exercises are of importance to brain remodeling, support neuronal survival and 
      positively affect rehabilitation therapy. Physical activity should be employed as 
      a tool to improve neural function in healthy subjects and in patients suffering 
      from neurological damage.
FAU - Achiron, Anat
AU  - Achiron A
AD  - Multiple Sclerosis Center, Sheba Medical Center, Tel-Hashomer, Israel. 
      achiron@post.tau.ac.il
FAU - Kalron, Alon
AU  - Kalron A
LA  - heb
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Israel
TA  - Harefuah
JT  - Harefuah
JID - 0034351
SB  - IM
MH  - Brain/*physiology
MH  - *Exercise
MH  - Humans
MH  - Motor Activity
MH  - Nervous System Diseases/physiopathology/rehabilitation
MH  - *Neuronal Plasticity
MH  - Synaptic Transmission/physiology
RF  - 28
EDAT- 2008/05/21 09:00
MHDA- 2008/08/12 09:00
CRDT- 2008/05/21 09:00
PHST- 2008/05/21 09:00 [pubmed]
PHST- 2008/08/12 09:00 [medline]
PHST- 2008/05/21 09:00 [entrez]
PST - ppublish
SO  - Harefuah. 2008 Mar;147(3):252-5, 276.