PMID- 18490857
OWN - NLM
STAT- MEDLINE
DCOM- 20080909
LR  - 20190911
IS  - 1347-8613 (Print)
IS  - 1347-8613 (Linking)
VI  - 107
IP  - 1
DP  - 2008 May
TI  - Effects of bemiparin, dalteparin, and unfractionated heparin on platelet 
      interaction with human subendothelium under flow conditions.
PG  - 103-6
AB  - We compared the effects of the low-molecular-weight heparin (LMWH), bemiparin, 
      and dalteparin with unfractionated heparin (UFH) on the platelet subendothelium 
      interaction under flow conditions. All three compounds decreased the percentage 
      of subendothelial matrix covered by platelets, although the effect of LMWH was 
      greater than that of UFH. Subendothelial matrix covered with platelet structures 
      greater than 100 square microns was significantly reduced by all three compounds; 
      the effect of bemiparin tended to be greater than that of the other two heparins.
FAU - Gonzalez-Correa, Jose Antonio
AU  - Gonzalez-Correa JA
AD  - Department of Pharmacology and Therapeutics, School of Medicine, University of 
      Malaga, Spain.
FAU - Arrebola, Maria Monsalud
AU  - Arrebola MM
FAU - Merida, Francisco
AU  - Merida F
FAU - Navas, Maria Dolores
AU  - Navas MD
FAU - Lopez-Villodres, Juan Antonio
AU  - Lopez-Villodres JA
FAU - Samanes, Felisa
AU  - Samanes F
FAU - Cruz, Jose Pedro De La
AU  - Cruz JP
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - J Pharmacol Sci
JT  - Journal of pharmacological sciences
JID - 101167001
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
RN  - PUE0TO3XDR (bemiparin)
RN  - S79O08V79F (Dalteparin)
SB  - IM
MH  - Adult
MH  - Anticoagulants/*pharmacology
MH  - Blood Platelets/*drug effects
MH  - Cell Adhesion/drug effects
MH  - Cells, Cultured
MH  - Dalteparin/*pharmacology
MH  - Endothelial Cells/*drug effects
MH  - Heparin/*pharmacology
MH  - Heparin, Low-Molecular-Weight/*pharmacology
MH  - Humans
MH  - Male
MH  - Platelet Adhesiveness/*drug effects
MH  - Pulsatile Flow
MH  - Stress, Mechanical
EDAT- 2008/05/21 09:00
MHDA- 2008/09/10 09:00
CRDT- 2008/05/21 09:00
PHST- 2008/05/21 09:00 [pubmed]
PHST- 2008/09/10 09:00 [medline]
PHST- 2008/05/21 09:00 [entrez]
AID - JST.JSTAGE/jphs/08018SC [pii]
AID - 10.1254/jphs.08018sc [doi]
PST - ppublish
SO  - J Pharmacol Sci. 2008 May;107(1):103-6. doi: 10.1254/jphs.08018sc.