PMID- 18492072
OWN - NLM
STAT- MEDLINE
DCOM- 20090325
LR  - 20131121
IS  - 1399-0012 (Electronic)
IS  - 0902-0063 (Linking)
VI  - 22
IP  - 5
DP  - 2008 Sep-Oct
TI  - Excellent outcome using "impaired" standard criteria donors with elevated serum 
      creatinine.
PG  - 630-3
LID - 10.1111/j.1399-0012.2008.00835.x [doi]
AB  - INTRODUCTION: To maximize organ utilization, the United Network for Organ Sharing 
      (UNOS) encourages use of Expanded Criteria Donors (ECD). However, Standard 
      Criteria Donors (SCD) may also be under-utilized, some centers discarding kidneys 
      with serum creatinine (S.Cr) >2.0 at nephrectomy. Our experience with the use of 
      such "impaired'' kidneys was reviewed retrospectively. RESULTS: From January 1, 
      2003 to October 1, 2006, of 130 DD kidneys transplanted at our center, 26 were 
      ECD. Also, 22 kidneys were from Impaired SCD (ISCD), with mean S.Cr 3.2 (2.1-4.4) 
      at nephrectomy; eight of these had S.Cr >4.0. For these 22 ISCD, mean age was 22 
      yrs (11-42), sex: 16 Males; race:12 Caucasians/10 African-Americans; All had 
      evidence of rhabdomyolysis (Mean peak CPK 11,924 u/l). Thirty-seven percent came 
      from outside OPOs. Recipient demographics: age 45 years; sex 50% male, 45% 
      African-American. Mean HLA match was 1; dialysis was required in 28% within the 
      first week. Mean length of stay was 10.7 days. Average discharge S.Cr was 4.2. 
      All kidneys are currently functioning (S.Cr at 3 months, 6 months and 1 year 1.6, 
      1.7 and 1.7 respectively). CONCLUSION: An elevated creatinine should not be the 
      only cause for discarding deceased donor kidneys.
FAU - Greenstein, Stuart M
AU  - Greenstein SM
AD  - Department of Surgery, Kidney Transplant Program, Montefiore Medical Center - the 
      University Hospital for the Albert Einstein College of Medicine, Bronx, NY, USA.
FAU - Moore, Norman
AU  - Moore N
FAU - McDonough, Patricia
AU  - McDonough P
FAU - Schechner, Richard
AU  - Schechner R
FAU - Tellis, Vivian
AU  - Tellis V
LA  - eng
PT  - Journal Article
DEP - 20080519
PL  - Denmark
TA  - Clin Transplant
JT  - Clinical transplantation
JID - 8710240
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Creatinine/*blood
MH  - Donor Selection/*standards
MH  - Female
MH  - Follow-Up Studies
MH  - Graft Survival
MH  - Humans
MH  - *Kidney Transplantation
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Rhabdomyolysis/blood
MH  - Tissue and Organ Procurement/*standards
MH  - Young Adult
EDAT- 2008/05/22 09:00
MHDA- 2009/03/26 09:00
CRDT- 2008/05/22 09:00
PHST- 2008/05/22 09:00 [pubmed]
PHST- 2009/03/26 09:00 [medline]
PHST- 2008/05/22 09:00 [entrez]
AID - CTR835 [pii]
AID - 10.1111/j.1399-0012.2008.00835.x [doi]
PST - ppublish
SO  - Clin Transplant. 2008 Sep-Oct;22(5):630-3. doi: 10.1111/j.1399-0012.2008.00835.x. 
      Epub 2008 May 19.