PMID- 18494429
OWN - NLM
STAT- MEDLINE
DCOM- 20080711
LR  - 20161124
IS  - 1474-9114 (Print)
IS  - 1474-9114 (Linking)
VI  - 18
IP  - 1
DP  - 2008
TI  - New guidelines for managing cow's milk allergy in infants.
PG  - 27-30
AB  - The prevalence of allergic disease has increased markedly over the last 50 years. 
      Food allergy usually manifests in early childhood as part of the so-called atopic 
      march and most commonly includes one or more of the following foods: cow's milk, 
      hen's egg, soy, peanuts and tree nuts, wheat, sesame seed, kiwi fruit and 
      seafood. In the UK about 2% of infants develop cow's milk protein allergy (CMPA), 
      but as many as 15% of infants present with symptoms suggestive of an adverse 
      reaction to cow's milk protein. The diagnosis of CMPA is based on one or more of 
      the following: a detailed clinical history, allergy test results (skin prick 
      testing [SPT] and/or specific immunoglobulin E [IgE]) and, if required, 
      supervised incremental milk challenges. The majority of UK primary care centres 
      do not have access to these tests and may also be unfamiliar with the 
      interpretation or results. In addition, they do not have the facilities for 
      supervised food challenges. Empirical treatment is often required pending 
      confirmation of allergy or referral to a specialist centre, but requires clear 
      guidelines. No consensus guidelines currently exist for the diagnosis and 
      management of CMPA in the UK. An international task force has recently published 
      proposed guidelines for the management of CMPA. These provide separate algorithms 
      covering the diagnosis and management of CMPA for both breast-fed and formula-fed 
      infants and discuss the use of hypoallergenic formulae, elimination diets and 
      diagnostic tests. Revisions and adaptations for the UK market are required and 
      are discussed in this article.
FAU - Meyer, Rosan
AU  - Meyer R
AD  - Department of Paediatrics, Imperial College, London.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - J Fam Health Care
JT  - The journal of family health care
JID - 101142028
MH  - *Algorithms
MH  - Allergy and Immunology
MH  - Animals
MH  - Bottle Feeding
MH  - Breast Feeding
MH  - Cattle
MH  - Community Health Nursing
MH  - Critical Pathways
MH  - *Decision Trees
MH  - Family Practice
MH  - Humans
MH  - Infant
MH  - Infant Food/adverse effects/supply & distribution
MH  - Milk Hypersensitivity/classification/*diagnosis/epidemiology/*therapy
MH  - *Practice Guidelines as Topic
MH  - Prevalence
MH  - Primary Health Care
MH  - Referral and Consultation
MH  - United Kingdom/epidemiology
RF  - 30
EDAT- 2008/05/23 09:00
MHDA- 2008/07/12 09:00
CRDT- 2008/05/23 09:00
PHST- 2008/05/23 09:00 [pubmed]
PHST- 2008/07/12 09:00 [medline]
PHST- 2008/05/23 09:00 [entrez]
PST - ppublish
SO  - J Fam Health Care. 2008;18(1):27-30.