PMID- 18501125
OWN - NLM
STAT- MEDLINE
DCOM- 20080911
LR  - 20190823
IS  - 0025-7753 (Print)
IS  - 0025-7753 (Linking)
VI  - 130
IP  - 17
DP  - 2008 May 10
TI  - Strict control of modifiable cardiovascular risk factors in patients with type 2 
      diabetes mellitus.
PG  - 641-4
AB  - BACKGROUND AND OBJECTIVE: To assess the effect of a strict control of modifiable 
      cardiovascular risk factors on coronary risk (CR) in patients with type 2 
      diabetes mellitus (T2DM) in clinical practice. PATIENTS AND METHOD: Longitudinal, 
      open and observational study in 530 patients with T2DM. Fasting plasma glucose 
      (FPG), glycated haemoglobin (HbA 1C), postprandial capillary glucose (PCG), total 
      cholesterol, high-density lipoprotein-cholesterol, triglycerides, systolic (SBP) 
      and diastolic (DBP) blood pressure were measured; low-density 
      lipoprotein-cholesterol and body mass index were calculated; and 10 years CR was 
      predicted before and after 6 months of therapy implementation. The percentage of 
      patients who reached the targets, according to published guidelines, and the use 
      of insulin and various cardioprotective medications were compared before and 
      after therapy implementation. RESULTS: There was a significant decrease in mean 
      HbA 1C, FPG, PCG, total cholesterol, triglycerides, SBP, DBP, and CR after 
      intervention. The percentage of patients who reached the HbA 1C, FPG, PCG, total 
      cholesterol, triglycerides, SBP, DPB, and CR targets, and the number of subjects 
      taking insulin and cardioprotective drugs increased significantly after 
      intervention. CONCLUSIONS: This study shows that a strict control of modifiable 
      cardiovascular risk factors in patients with T2DM in clinical practice has a 
      beneficial effect over predicted CR.
FAU - del Canizo Gomez, Francisco Javier
AU  - del Canizo Gomez FJ
AD  - Unidad de Endocrinologia, Hospital Virgen de la Torre, Madrid, Espana. 
      fjcanizo@arrakis.es
FAU - Moreira Andres, Maria Natividad
AU  - Moreira Andres MN
LA  - eng
PT  - Journal Article
PL  - Spain
TA  - Med Clin (Barc)
JT  - Medicina clinica
JID - 0376377
RN  - 0 (Angiotensin-Converting Enzyme Inhibitors)
RN  - 0 (Insulin)
SB  - IM
MH  - Aged
MH  - Angiotensin-Converting Enzyme Inhibitors
MH  - Anthropometry
MH  - Body Mass Index
MH  - Cardiovascular Diseases/drug therapy/*epidemiology
MH  - Diabetes Mellitus, Type 2/drug therapy/*epidemiology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Insulin/therapeutic use
MH  - Male
MH  - Risk Factors
EDAT- 2008/05/27 09:00
MHDA- 2008/09/13 09:00
CRDT- 2008/05/27 09:00
PHST- 2008/05/27 09:00 [pubmed]
PHST- 2008/09/13 09:00 [medline]
PHST- 2008/05/27 09:00 [entrez]
AID - S0025-7753(08)71534-3 [pii]
AID - 10.1157/13120691 [doi]
PST - ppublish
SO  - Med Clin (Barc). 2008 May 10;130(17):641-4. doi: 10.1157/13120691.