PMID- 18516824 OWN - NLM STAT- MEDLINE DCOM- 20080919 LR - 20161124 IS - 0019-5707 (Print) IS - 0019-5707 (Linking) VI - 55 IP - 2 DP - 2008 Apr TI - Clinico-radiological profile of new smear positive pulmonary tuberculosis cases among young adult and elderly people in a tertiary care hospital at Deheradun (Uttarakhand). PG - 84-90 AB - SETTING: Patients of pulmonary tuberculosis (TB) attending the out and in patient department of pulmonary medicine, Himalayan Institute of Medical Sciences (HIMS), a post graduate institute and a large tertiary care center in Dehradun. OBJECTIVE: To compare the clinico-radiological pattern of pulmonary tuberculosis in the young adult (18-59 years) and elderly (> or = 60 years) patients. DESIGN: Prospective observational study of pulmonary and associated extra pulmonary tuberculosis cases, diagnosed between October 2005 to September 2006 in pulmonary medicine department of HIMS. RESULT: Mean age of young adult and elderly patients was 35.71 +/- 5.7 years and 68.57 +/- 3.03 years respectively. Elderly patients had a higher number of co-morbidities like diabetes mellitus, hypertension, and malignancy. Tuberculin positivity was less among elderly patients (36.0%) as compared to young adults (65.9%). Hemoptysis (29.5% vs. 6%), fever (95.4% vs. 76%) and night sweats (54.5% vs. 18.0%) were significantly higher in the young adult patients than the elderly. As for roentgenographic abnormalities, a higher involvement of lower zone (24.0% vs. 7.9%) and far advanced lesions (32.0% vs. 14.7%) were seen in the elderly patients as compared to young adults. The elderly showed a higher frequency of TB related mortality (8% vs. 1.1%) and associated extra pulmonary involvement (40% vs. 7%). CONCLUSION: Young adults are more likely to have hemoptysis, night sweats and positive PPD response while lower lung field involvement is more common in elderly. FAU - Rawat, Jagdish AU - Rawat J AD - Department of Community Medicine, Himalayan Institute of Medical Sciences, Dehradun. drjagdishrawat@yahoo.com FAU - Sindhwani, Girish AU - Sindhwani G FAU - Juyal, Ruchi AU - Juyal R LA - eng PT - Comparative Study PT - Journal Article PL - India TA - Indian J Tuberc JT - The Indian journal of tuberculosis JID - 0373027 SB - IM MH - Academic Medical Centers MH - Adult MH - Age Factors MH - Aged MH - Comorbidity MH - Diabetes Mellitus/epidemiology MH - Female MH - Fever/epidemiology MH - Hemoptysis/epidemiology MH - Humans MH - Hypertension/epidemiology MH - India/epidemiology MH - Male MH - Neoplasms/epidemiology MH - Prospective Studies MH - Radiography MH - Survival Rate MH - Tuberculin Test/statistics & numerical data MH - Tuberculosis, Pulmonary/*diagnosis/diagnostic imaging/*epidemiology EDAT- 2008/06/04 09:00 MHDA- 2008/09/20 09:00 CRDT- 2008/06/04 09:00 PHST- 2008/06/04 09:00 [pubmed] PHST- 2008/09/20 09:00 [medline] PHST- 2008/06/04 09:00 [entrez] PST - ppublish SO - Indian J Tuberc. 2008 Apr;55(2):84-90.