PMID- 18534237 OWN - NLM STAT- MEDLINE DCOM- 20080813 LR - 20221207 IS - 1097-6833 (Electronic) IS - 0022-3476 (Linking) VI - 153 IP - 2 DP - 2008 Aug TI - Relationship between body mass index and metabolic syndrome risk factors among US 8- to 14-year-olds, 1999 to 2002. PG - 215-21 LID - 10.1016/j.jpeds.2008.03.002 [doi] AB - OBJECTIVES: To determine the prevalence of metabolic syndrome risk factors (MSRF) and examine the relationship between body mass index and the prevalence of >or=3 MSRF in 8- to 11- and 12- to 14-year-old age groups. STUDY DESIGN: Combined 1999 to 2002 National Health and Nutrition Examination Survey data were analyzed (N = 1698). Prevalence of normal weight, at-risk for overweight, and overweight were determined. Prevalence of >or=3 MSRF (abnormal waist circumference, glucose, HDL cholesterol, triglyceride, systolic and diastolic blood pressure) were reported using (1) an age, sex, and ethnicity-adjusted and (2) a crude profile (no adjustments). RESULTS: Among overweight 8- to 11-year-old children, 6.5% (95% CI, 3.82 to 10.86) had >or=3 MSRF using the crude profile and 9.51% (95% CI 5.59 to 15.71) using the adjusted profile. Among overweight 12- to 14-year-olds, 43.76% (95% CI, 33.27 to 54.85) had >or=3 MSRF using the crude profile and 26.28% (95% CI, 16.71 to 38.78) using the adjusted profile. CONCLUSIONS: A substantial number of overweight 8- to 14-year-olds have >or=3 MSRF, indicating that overweight in early adolescence may put children at risk for adult-onset cardiovascular disease and/or type 2 diabetes well before they become teenagers. FAU - Messiah, Sarah E AU - Messiah SE AD - Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33101, USA. smessiah@med.miami.edu FAU - Arheart, Kristopher L AU - Arheart KL FAU - Luke, Barbara AU - Luke B FAU - Lipshultz, Steven E AU - Lipshultz SE FAU - Miller, Tracie L AU - Miller TL LA - eng PT - Journal Article DEP - 20080418 PL - United States TA - J Pediatr JT - The Journal of pediatrics JID - 0375410 SB - IM MH - Adolescent MH - Black or African American/statistics & numerical data MH - *Body Mass Index MH - Causality MH - Child MH - Comorbidity MH - Female MH - Humans MH - Male MH - Metabolic Syndrome/*epidemiology MH - Mexican Americans/statistics & numerical data MH - Nutrition Surveys MH - Overweight/epidemiology MH - Prevalence MH - Risk Factors MH - United States/epidemiology MH - White People/statistics & numerical data EDAT- 2008/06/07 09:00 MHDA- 2008/08/14 09:00 CRDT- 2008/06/07 09:00 PHST- 2007/09/13 00:00 [received] PHST- 2008/01/18 00:00 [revised] PHST- 2008/03/04 00:00 [accepted] PHST- 2008/06/07 09:00 [pubmed] PHST- 2008/08/14 09:00 [medline] PHST- 2008/06/07 09:00 [entrez] AID - S0022-3476(08)00187-X [pii] AID - 10.1016/j.jpeds.2008.03.002 [doi] PST - ppublish SO - J Pediatr. 2008 Aug;153(2):215-21. doi: 10.1016/j.jpeds.2008.03.002. Epub 2008 Apr 18.