PMID- 18536317
OWN - NLM
STAT- MEDLINE
DCOM- 20080729
LR  - 20131121
IS  - 0301-4894 (Print)
IS  - 0301-4894 (Linking)
VI  - 109
IP  - 3
DP  - 2008 May
TI  - [Recent advances in treatment of pancreatic neuroendocrine tumors].
PG  - 143-6
AB  - The recent consensus on the diagnosis and treatment of pancreatic neuroendocrine 
      tumors (PNET) is described. The selective arterial secretagogue injection test 
      and somatostatin receptor scintigraphy are essential for the localization of 
      PNET. A few characteristic clinicopathologic findings of PNET in patients with 
      multiple endocrine neoplasia type 1 (MEN 1) have been elucidated and contributed 
      to improved surgical treatment for these tumors, such as pancreas-preserving 
      total duodenectomy for multiple duodenal gastrinomas in patients with MEN 1 and 
      Zollinger-Ellison syndromes, or distal pancreatectomy for patients with MEN 1 and 
      hypoglycemia. Early diagnosis and early surgical resection of PNET are 
      recommended for complete cure of disease. In liver metastasis of PNET, mass 
      reduction surgery with hepatectomy improves the prognosis of patients, and 
      octreotide LAR has been shown to be useful for reducing complications and 
      inhibiting the growth of tumors.
FAU - Imamura, Masayuki
AU  - Imamura M
AD  - Kyoto University, Osaka, Japan.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Geka Gakkai Zasshi
JT  - Nihon Geka Gakkai zasshi
JID - 0405405
RN  - 0 (Antineoplastic Agents, Hormonal)
RN  - RWM8CCW8GP (Octreotide)
SB  - IM
MH  - Antineoplastic Agents, Hormonal/therapeutic use
MH  - Diagnostic Imaging
MH  - Humans
MH  - Laparoscopy
MH  - Neuroendocrine Tumors/diagnosis/*therapy
MH  - Octreotide/therapeutic use
MH  - Pancreatic Neoplasms/diagnosis/*therapy
RF  - 18
EDAT- 2008/06/10 09:00
MHDA- 2008/07/30 09:00
CRDT- 2008/06/10 09:00
PHST- 2008/06/10 09:00 [pubmed]
PHST- 2008/07/30 09:00 [medline]
PHST- 2008/06/10 09:00 [entrez]
PST - ppublish
SO  - Nihon Geka Gakkai Zasshi. 2008 May;109(3):143-6.