PMID- 18540370 OWN - NLM STAT- MEDLINE DCOM- 20080729 LR - 20110727 IS - 0047-1852 (Print) IS - 0047-1852 (Linking) VI - 66 IP - 6 DP - 2008 Jun TI - [Apheresis therapy in Guillain-Barre syndrome]. PG - 1195-9 AB - Based on previous randomized controlled-trials (RCTs), plasma exchange (PE) has been established as an effective treatment for Guillain-Barre syndrome (GBS). Double filtration plasmapheresis (DFPP) and immunoadsorption plasmapheresis (IAPP) may be effective for GBS, however their effectiveness have not been established because any RCTs have not been available so far. Intravenous immunoglobulin (IVIG) has also been established to be effective for GBS according to several RCTs, however complications have been more frequent in PE than IVIG. Therefore IVIg treatment should be considered as the first choice for GBS, and PE treatment remains as the second-line if IVIg treatment is contraindicated. FAU - Nagayama, Hiroshi AU - Nagayama H AD - Department of Internal Medicine, Nippon Medical School. FAU - Katayama, Yasuo AU - Katayama Y LA - jpn PT - English Abstract PT - Journal Article PT - Review PL - Japan TA - Nihon Rinsho JT - Nihon rinsho. Japanese journal of clinical medicine JID - 0420546 SB - IM MH - *Blood Component Removal MH - Guillain-Barre Syndrome/*therapy MH - Humans MH - Plasma Exchange MH - Plasmapheresis RF - 10 EDAT- 2008/06/11 09:00 MHDA- 2008/07/30 09:00 CRDT- 2008/06/11 09:00 PHST- 2008/06/11 09:00 [pubmed] PHST- 2008/07/30 09:00 [medline] PHST- 2008/06/11 09:00 [entrez] PST - ppublish SO - Nihon Rinsho. 2008 Jun;66(6):1195-9.