PMID- 18564209 OWN - NLM STAT- MEDLINE DCOM- 20090303 LR - 20181201 IS - 1610-0387 (Electronic) IS - 1610-0379 (Linking) VI - 6 IP - 10 DP - 2008 Oct TI - Subacute cutaneous lupus erythematosus induced by terbinafine: case report and review of literature. PG - 823-7, 823-8 LID - 10.1111/j.1610-0387.2008.06806.x [doi] AB - Systemic lupus erythematosus and subacute cutaneous lupus erythematosus (SCLE) occasionally evolve as adverse reactions to a large variety of chemically different drugs. We here report on a 76-year-old woman who developed SCLE within 10 days after initiation of oral terbinafine. Analysis of the 27 cases of terbinafine-induced SCLE in the literature revealed that this disorder has been reported 6 times more often in females than in males. Skin lesions evolved on average around 7 weeks after starting the drug. In 79% of the cases ANA could be detected while antibodies against Ro/SS-A and La/SS-B were found in 86% and 39%, respectively. Remarkably, anti-histone antibodies were present in only 29%. In all cases terbinafine-induced SCLE resolved after discontinuation of the triggering agent. Systemic treatment with anti-malarials and/or corticosteroids does not appear to be mandatory. FAU - Lorentz, Katharina AU - Lorentz K AD - Department of Dermatology, University Clinic of Mannheim, Medical School of Mannheim at the University of Heidelberg, Germany. FAU - Booken, Nina AU - Booken N FAU - Goerdt, Sergij AU - Goerdt S FAU - Goebeler, Matthias AU - Goebeler M LA - eng LA - ger PT - Case Reports PT - Journal Article PT - Review DEP - 20080617 PL - Germany TA - J Dtsch Dermatol Ges JT - Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG JID - 101164708 RN - 0 (Antifungal Agents) RN - 0 (Naphthalenes) RN - G7RIW8S0XP (Terbinafine) SB - IM MH - Acute Disease MH - Aged MH - Antifungal Agents/*adverse effects MH - Drug Eruptions/*diagnosis/*etiology/therapy MH - Female MH - Humans MH - Lupus Erythematosus, Cutaneous/*chemically induced/*diagnosis/therapy MH - Naphthalenes/*adverse effects MH - Terbinafine RF - 17 EDAT- 2008/06/20 09:00 MHDA- 2009/03/04 09:00 CRDT- 2008/06/20 09:00 PHST- 2008/06/20 09:00 [pubmed] PHST- 2009/03/04 09:00 [medline] PHST- 2008/06/20 09:00 [entrez] AID - DDG06806 [pii] AID - 10.1111/j.1610-0387.2008.06806.x [doi] PST - ppublish SO - J Dtsch Dermatol Ges. 2008 Oct;6(10):823-7, 823-8. doi: 10.1111/j.1610-0387.2008.06806.x. Epub 2008 Jun 17.