PMID- 18564319
OWN - NLM
STAT- MEDLINE
DCOM- 20091026
LR  - 20090727
IS  - 1439-0531 (Electronic)
IS  - 0936-6768 (Linking)
VI  - 44
IP  - 4
DP  - 2009 Aug
TI  - Effect of oxytocin treatment on artificial insemination with frozen-thawed semen 
      in Murciano-Granadina goats.
PG  - 576-9
LID - 10.1111/j.1439-0531.2007.00993.x [doi]
AB  - The site where the semen is deposited appears to be one of the most important 
      factors affecting pregnancy of inseminated goats. In Murciano-Granadina (MG) 
      goats, post-cervical insemination is achieved in a limited number of females. An 
      effective way to increase fertility rate could be by increasing post-cervical 
      inseminations. Effect of exogenous oxytocin application to facilitate the 
      cervical penetration and its effect on kidding rate and prolificacy in MG goats 
      were investigated. Oestrus was synchronized using progesterone-impregnated 
      sponges for 11 days. Females were randomly divided into three groups (n = 190) 
      and received either an i.v. injection of 100 or 200 IU of oxytocin or saline 
      solution 15 min before being inseminated. Data on semen deposition depth were 
      recorded for each animal using a catheter scaled in centimetres (up to 4 cm). 
      Depth of semen deposition was affected by the oxytocin treatment (p < 0.05). 
      Oxytocin enhanced cervical passage only with the dose of 200 IU compared with the 
      control group, increasing the deposition depth (2.9 cm vs 1.9 cm). No significant 
      effect of oxytocin treatment on kidding rate and prolificacy was detected. Depth 
      of semen deposition affected kidding rate (p < 0.01). In conclusion, oxytocin 
      treatment improved the depth of semen deposition in AI of MG goats, but kidding 
      rate and prolificacy was not affected. More studies must be conducted to assess 
      the minimal effective dose required for sufficient cervical dilation, and to 
      determine the effects of such doses of oxytocin on uterine motility, sperm 
      transport and fertility in goats.
FAU - Viudes-de-Castro, M P
AU  - Viudes-de-Castro MP
AD  - Centro de Tecnologia Animal, Instituto Valenciano de Investigaciones Agrarias 
      (CITA-IVIA), Valencia, Spain. mpviudes@ivia.es
FAU - Salvador, I
AU  - Salvador I
FAU - Marco-Jimenez, F
AU  - Marco-Jimenez F
FAU - Gomez, E A
AU  - Gomez EA
FAU - Silvestre, M A
AU  - Silvestre MA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080628
PL  - Germany
TA  - Reprod Domest Anim
JT  - Reproduction in domestic animals = Zuchthygiene
JID - 9015668
RN  - 50-56-6 (Oxytocin)
SB  - IM
MH  - Animals
MH  - Cervix Uteri/anatomy & histology/drug effects
MH  - Cryopreservation/*veterinary
MH  - Estrus Synchronization
MH  - Female
MH  - Goats/*physiology
MH  - Hot Temperature
MH  - Injections, Intravenous/veterinary
MH  - Insemination, Artificial/methods/*veterinary
MH  - Male
MH  - Oxytocin/*administration & dosage
MH  - Pregnancy
MH  - Semen Preservation/*veterinary
EDAT- 2008/06/20 09:00
MHDA- 2009/10/27 06:00
CRDT- 2008/06/20 09:00
PHST- 2008/06/20 09:00 [pubmed]
PHST- 2009/10/27 06:00 [medline]
PHST- 2008/06/20 09:00 [entrez]
AID - RDA993 [pii]
AID - 10.1111/j.1439-0531.2007.00993.x [doi]
PST - ppublish
SO  - Reprod Domest Anim. 2009 Aug;44(4):576-9. doi: 10.1111/j.1439-0531.2007.00993.x. 
      Epub 2008 Jun 28.