PMID- 18566178
OWN - NLM
STAT- MEDLINE
DCOM- 20080718
LR  - 20191210
IS  - 1527-1315 (Electronic)
IS  - 0033-8419 (Linking)
VI  - 248
IP  - 1
DP  - 2008 Jul
TI  - Liver imaging at 3.0 T: diffusion-induced black-blood echo-planar imaging with 
      large anatomic volumetric coverage as an alternative for specific absorption 
      rate-intensive echo-train spin-echo sequences: feasibility study.
PG  - 264-71
LID - 10.1148/radiol.2481070034 [doi]
AB  - Institutional Review Board approval and signed informed consent were obtained by 
      all participants for an ongoing sequence optimization project at 3.0 T. The 
      purpose of this study was to evaluate breath-hold diffusion-induced black-blood 
      echo-planar imaging (BBEPI) as a potential alternative for specific absorption 
      rate (SAR)-intensive spin-echo sequences, in particular, the fast spin-echo (FSE) 
      sequences, at 3.0 T. Fourteen healthy volunteers (seven men, seven women; mean 
      age +/- standard deviation, 32.7 years +/- 6.8) were imaged for this purpose. 
      Liver coverage (20 cm, z-axis) was always performed in one 25-second breath hold. 
      Imaging parameters were varied interactively with regard to echo time, diffusion 
      b value, and voxel size. Images were evaluated and compared with fat-suppressed 
      T2-weighted FSE images for image quality, liver delineation, geometric 
      distortions, fat suppression, suppression of the blood signal, contrast-to-noise 
      ratio (CNR), and signal-to-noise ratio (SNR). An optimized short- (25 msec) and 
      long-echo (80 msec) BBEPI provided full anatomic, single breath-hold liver 
      coverage (100 and 50 sections, respectively), with resulting voxel sizes of 3.3 x 
      2.7 x 2.0 mm and 3.3 x 2.7 x 4.0 mm, respectively. Repetition time was 6300 msec, 
      matrix size was 160 x 192, and an acceleration factor of 2.00 was used. b Values 
      of more than 20 sec/mm(2) showed better suppression of the blood signal but b 
      values of 10 sec/mm(2) provided improved volume coverage and signal consistency. 
      Compared with fat-suppressed T2-weighted FSE, the optimized BBEPI sequence 
      provided (a) comparable image quality and liver delineation, (b) acceptable 
      geometric distortions, (c) improved suppression of fat and blood signals, and (d) 
      high CNR and SNR. BBEPI is feasible for fast, low-SAR, thin-section morphologic 
      imaging of the entire liver in a single breath hold at 3.0 T.
CI  - (c) RSNA, 2008.
FAU - van den Bos, Indra C
AU  - van den Bos IC
AD  - Department of Radiology, Erasmus MC, University Medical Center-Rotterdam, Dr 
      Molewaterplein 40, 3015 GD Rotterdam, the Netherlands. vandenbos.ic@gmail.com
FAU - Hussain, Shahid M
AU  - Hussain SM
FAU - Krestin, Gabriel P
AU  - Krestin GP
FAU - Wielopolski, Piotr A
AU  - Wielopolski PA
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
SB  - IM
MH  - Adult
MH  - *Algorithms
MH  - Diffusion Magnetic Resonance Imaging/*methods
MH  - Echo-Planar Imaging/*methods
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Imaging, Three-Dimensional/*methods
MH  - Liver/*anatomy & histology
MH  - Male
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2008/06/21 09:00
MHDA- 2008/07/19 09:00
CRDT- 2008/06/21 09:00
PHST- 2008/06/21 09:00 [pubmed]
PHST- 2008/07/19 09:00 [medline]
PHST- 2008/06/21 09:00 [entrez]
AID - 248/1/264 [pii]
AID - 10.1148/radiol.2481070034 [doi]
PST - ppublish
SO  - Radiology. 2008 Jul;248(1):264-71. doi: 10.1148/radiol.2481070034.