PMID- 18581115
OWN - NLM
STAT- MEDLINE
DCOM- 20090406
LR  - 20211020
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Linking)
VI  - 18
IP  - 12
DP  - 2008 Dec
TI  - Contrast-enhanced cardiac MRI before coronary artery bypass surgery: impact of 
      myocardial scar extent on bypass flow.
PG  - 2756-64
LID - 10.1007/s00330-008-1066-y [doi]
AB  - The aim of the study was to relate the extent of myocardial late gadolinium 
      enhancement (LGE) in cardiac MRI to intraoperative graft flow in patients 
      undergoing coronary artery bypass graft (CABG) surgery. Thirty-three CAD patients 
      underwent LGE MRI before surgery using an inversion-recovery GRE sequence 
      (turboFLASH). Intraoperative graft flow in Doppler ultrasonography was compared 
      with the scar extent in each coronary vessel territory. One hundred and fourteen 
      grafts were established supplying 86 of the 99 vessel territories. A significant 
      negative correlation was found between scar extent and graft flow (r = -0.4, p < 
      0.0001). Flow in grafts to territories with no or small subendocardial scar was 
      significantly higher than in grafts to territories with broad nontransmural or 
      transmural scar (75 +/- 39 vs. 38 +/- 26 cc min(-1); p < 0.0001). In summary, the 
      extent of myocardial scar as defined by contrast-enhanced MRI predicts coronary 
      bypass graft flow. Beyond the probability of functional recovery, preoperative 
      MRI might add value to surgery planning by predicting midterm bypass graft 
      patency.
FAU - Hunold, Peter
AU  - Hunold P
AD  - Department of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 
      45122, Essen, Germany. peter.hunold@uk-essen.de
FAU - Massoudy, Parwis
AU  - Massoudy P
FAU - Boehm, Claudia
AU  - Boehm C
FAU - Schlosser, Thomas
AU  - Schlosser T
FAU - Nassenstein, Kai
AU  - Nassenstein K
FAU - Knipp, Stephan
AU  - Knipp S
FAU - Eggebrecht, Holger
AU  - Eggebrecht H
FAU - Thielmann, Matthias
AU  - Thielmann M
FAU - Erbel, Raimund
AU  - Erbel R
FAU - Jakob, Heinz
AU  - Jakob H
FAU - Barkhausen, Jorg
AU  - Barkhausen J
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20080626
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Aged
MH  - Blood Flow Velocity
MH  - Contrast Media
MH  - Coronary Artery Bypass/*methods
MH  - Coronary Vessels/*pathology/*surgery
MH  - Female
MH  - *Gadolinium DTPA
MH  - Graft Survival
MH  - Humans
MH  - Image Enhancement/methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Myocardial Stunning/*diagnosis/*surgery
MH  - Preoperative Care/methods
MH  - Prognosis
EDAT- 2008/06/27 09:00
MHDA- 2009/04/07 09:00
CRDT- 2008/06/27 09:00
PHST- 2008/01/21 00:00 [received]
PHST- 2008/05/20 00:00 [accepted]
PHST- 2008/04/12 00:00 [revised]
PHST- 2008/06/27 09:00 [pubmed]
PHST- 2009/04/07 09:00 [medline]
PHST- 2008/06/27 09:00 [entrez]
AID - 10.1007/s00330-008-1066-y [doi]
PST - ppublish
SO  - Eur Radiol. 2008 Dec;18(12):2756-64. doi: 10.1007/s00330-008-1066-y. Epub 2008 
      Jun 26.