PMID- 1858622
OWN - NLM
STAT- MEDLINE
DCOM- 19910829
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 122
IP  - 2
DP  - 1991 Aug
TI  - Effect of the degree of effort on exercise echocardiography for the detection of 
      restenosis after coronary artery angioplasty.
PG  - 430-7
AB  - To determine whether the accuracy of exercise echocardiography is affected by the 
      degree of effort during exercise, we examined 101 patients who had 6 months 
      earlier undergone successful coronary artery angioplasty, with resting and 
      immediate postexercise echocardiography and same-day coronary angiography. A 
      positive exercise echocardiographic response was defined as the development of a 
      new or worsening wall motion abnormality postexercise, compared with resting wall 
      motion. Significant coronary disease (greater than 50% diameter stenosis) was 
      present in 48 patients, 38 of whom had single-vessel disease and 10 of whom had 
      two-vessel disease. Exercise echocardiography correctly identified 32 patients 
      with significant disease (sensitivity 67%) and 44 patients without significant 
      disease (specificity 83%). The effect of the degree of exercise effort on the 
      sensitivity and specificity of the test was evaluated by three criteria; (1) the 
      percentage of maximum predicted heart rate (MHR), (2) the duration of exercise 
      (DUR), and (3) the double product (DP). To determine the influence of the degree 
      of effort upon sensitivity and specificity, the effort criteria were compared 
      between patients with true positive (TP) tests to those with false negative tests 
      (FN), and in patients with true negative (TN) tests compared with those with 
      false positive (FP) tests. No significant differences were detected in MHR, DUR, 
      or DP between TP versus FN patients or between TN versus FP patients. These 
      results indicate that for symptom-limited exercise echocardiography in 
      postangioplasty patients, neither sensitivity nor specificity is significantly 
      affected by the degree of effort during exercise.
FAU - Aboul-Enein, H
AU  - Aboul-Enein H
AD  - Department of Medicine Duke University Medical Center, Durham, NC 27710.
FAU - Bengston, J R
AU  - Bengston JR
FAU - Adams, D B
AU  - Adams DB
FAU - Mostafa, M A
AU  - Mostafa MA
FAU - Ibrahim, M M
AU  - Ibrahim MM
FAU - Hifny, A A
AU  - Hifny AA
FAU - Sheikh, K H
AU  - Sheikh KH
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
SB  - IM
MH  - *Angioplasty, Balloon, Coronary
MH  - Coronary Angiography
MH  - Coronary Disease/*diagnostic imaging/therapy
MH  - *Echocardiography
MH  - Electrocardiography
MH  - Evaluation Studies as Topic
MH  - Exercise/*physiology
MH  - Exercise Test
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Contraction/physiology
MH  - Recurrence
MH  - Sensitivity and Specificity
EDAT- 1991/08/01 00:00
MHDA- 1991/08/01 00:01
CRDT- 1991/08/01 00:00
PHST- 1991/08/01 00:00 [pubmed]
PHST- 1991/08/01 00:01 [medline]
PHST- 1991/08/01 00:00 [entrez]
AID - 0002-8703(91)90996-U [pii]
AID - 10.1016/0002-8703(91)90996-u [doi]
PST - ppublish
SO  - Am Heart J. 1991 Aug;122(2):430-7. doi: 10.1016/0002-8703(91)90996-u.