PMID- 18591848
OWN - NLM
STAT- MEDLINE
DCOM- 20080818
LR  - 20190606
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 47
IP  - 13
DP  - 2008
TI  - Type 1 diabetes mellitus associated with Graves' disease and Vogt-Koyanagi-Harada 
      syndrome.
PG  - 1241-4
AB  - A 30-year-old woman was diagnosed as having Vogt-Koyanagi-Harada (VKH) syndrome. 
      Her past history was Graves' disease. She was administered 1 g of 
      methylprednisolone for three days, which was followed by oral prednisolone. Four 
      weeks later, she developed hyperglycemic hyperosmolar coma. She was treated with 
      intravenous normal saline and insulin, and glycemic control was improved. She was 
      diagnosed as having type 1 diabetes mellitus (DM) because of positive test 
      results for glutamic acid decarboxylase (GAD) antibodies and islet cell 
      antibodies. Her human leukocyte antigen (HLA) genotypes were DQB1(*)0401 and 
      DRB1(*)0405, which were susceptible genes for VKH syndrome, type 1 DM and Graves' 
      disease. Therefore, we should consider that VKH syndrome might be associated with 
      type 1 DM or Graves' disease.
FAU - Suzuki, Hiroaki
AU  - Suzuki H
AD  - Department of Internal Medicine, The National Disaster Medical Center, Tachikawa, 
      Japan. hirosuzu@md.tsukuba.ac.jp
FAU - Isaka, Masaaki
AU  - Isaka M
FAU - Suzuki, Seiji
AU  - Suzuki S
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20080701
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DQ beta-Chains)
RN  - 0 (HLA-DQB1 antigen)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Adult
MH  - Diabetes Mellitus, Type 1/*complications/genetics
MH  - Female
MH  - Genetic Predisposition to Disease
MH  - Genotype
MH  - Graves Disease/*complications/genetics
MH  - HLA-DQ Antigens/genetics
MH  - HLA-DQ beta-Chains
MH  - HLA-DR Antigens/genetics
MH  - HLA-DRB1 Chains
MH  - Humans
MH  - Uveomeningoencephalitic Syndrome/*complications/genetics
EDAT- 2008/07/02 09:00
MHDA- 2008/08/19 09:00
CRDT- 2008/07/02 09:00
PHST- 2008/07/02 09:00 [pubmed]
PHST- 2008/08/19 09:00 [medline]
PHST- 2008/07/02 09:00 [entrez]
AID - JST.JSTAGE/internalmedicine/47.0715 [pii]
AID - 10.2169/internalmedicine.47.0715 [doi]
PST - ppublish
SO  - Intern Med. 2008;47(13):1241-4. doi: 10.2169/internalmedicine.47.0715. Epub 2008 
      Jul 1.