PMID- 18604114
OWN - NLM
STAT- MEDLINE
DCOM- 20081211
LR  - 20080708
IS  - 1812-2078 (Electronic)
IS  - 1812-2027 (Linking)
VI  - 6
IP  - 1
DP  - 2008 Jan-Mar
TI  - Diagnostic variability and therapeutic efficacy of ECT in Nepalese sample.
PG  - 41-8
AB  - BACKGROUND: Though electroconvulsive therapy (ECT) has been used in Nepal for 
      last twenty years, researches regarding its use, its efficacy and other data are 
      non-existent. AIMS: The objective of this study was to know about diagnostic 
      variability and therapeutic efficacy of the use of ECT in hospitalized patients. 
      METHODS: This is a prospective comparative study between patients who received 
      ECT and who did not using ICD-10 as diagnostic confirmation. Psychopathology was 
      evaluated using Brief Psychiatric Research Scale (BPRS), Hamilton Depression 
      Rating Scale (HAM-D) and Young Mania Rating Scale (YMRS) between the groups at 
      admission, at discharge, at 1st month, at 6th month and at 12th month. Functional 
      assessment of patients was done using Global Assessment of Function (GAF). 
      Modified ECT was performed using general anaesthetic agent. RESULTS: 47 patients 
      received ECT as compared to 78 patients who were non-receivers. The patients with 
      most common five diagnosis were paranoid schizophrenia (14.4%); psychotic 
      depression (13.6%) ; undifferentiated schizophrenia (8.8%) ; bipolar mania (7.2% 
      ) ;severe depression without psychosis (5.6%) . There was significant decrease in 
      BPRS in ECT receiver as compared to non-receivers at discharge (p=0.0001), 1st 
      month (p=0.0001), 6th month (p=0.0001) and 12th month (p=0.0001) ; in YMRS at 
      discharge (p=.008), 1st month (p=.002) and at 12th month (p=.015) ; in HAMD-M at 
      discharge (p=0.0001), at 1st month (p=0.0001), at 6th month (p=0.0001) and at 
      12th month (p=0.0001) ; in GAF at discharge (p=0.0001), at 6th month (p=0.0001) 
      and at 12th month (p=0.0001). CONCLUSION: There was significant improvement in 
      overall psychopathology of patients who received ECT as compared to 
      non-receivers. The improvement was shown by decrement in scores in BPRS, YMRS, 
      HDRS and GAF at the time of discharge, 1st month, 6th month and 12th month which 
      were statistically significant. Day to day functional status of patients also 
      improved as shown by GAF. The efficacy of ECT was very significantly shown in 
      this study with all the psychiatric spectrum disorders.
FAU - Ahikari, S R
AU  - Ahikari SR
AD  - Department of Psychiatry, Kathmandu Medical College, Sinamangal, Nepal. 
      mahit1971@yahoo.com
FAU - Pradhan, S N
AU  - Pradhan SN
FAU - Sharma, S C
AU  - Sharma SC
FAU - Shrestha, B R
AU  - Shrestha BR
FAU - Shrestha, S
AU  - Shrestha S
FAU - Tabedar, S
AU  - Tabedar S
LA  - eng
PT  - Journal Article
PL  - Nepal
TA  - Kathmandu Univ Med J (KUMJ)
JT  - Kathmandu University medical journal (KUMJ)
JID - 101215359
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Child
MH  - *Electroconvulsive Therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Mental Disorders/*diagnosis/*therapy
MH  - Middle Aged
MH  - Nepal
MH  - Prospective Studies
MH  - Psychiatric Status Rating Scales
MH  - Sex Distribution
MH  - Young Adult
EDAT- 2008/07/08 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/07/08 09:00
PHST- 2008/07/08 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/07/08 09:00 [entrez]
PST - ppublish
SO  - Kathmandu Univ Med J (KUMJ). 2008 Jan-Mar;6(1):41-8.