PMID- 18607172
OWN - NLM
STAT- MEDLINE
DCOM- 20081125
LR  - 20220408
IS  - 0954-6928 (Print)
IS  - 0954-6928 (Linking)
VI  - 19
IP  - 5
DP  - 2008 Aug
TI  - Coronary lesion type, location, and characteristics of acute ST elevation 
      myocardial infarction in young adults under 35 years of age.
PG  - 345-7
LID - 10.1097/MCA.0b013e3283030b3b [doi]
AB  - OBJECTIVE: In the present study, we attempted to analyze the coronary artery 
      lesion characteristics of acute ST elevation myocardial infarction (STEMI) in 
      young patients (aged less than 35 years). METHODS: We retrospectively surveyed 25 
      038 coronary angiography procedures, which were carried out at The Baskent 
      University Adana Hospital from 1998 to present, to discover acute STEMI in young 
      patients. We studied clinical risk factors and angiographic characteristics in 42 
      consecutive patients who underwent primary coronary angiography for acute STEMI. 
      Control group (n=42) had no history of coronary artery disease and had 
      angiographically proven normal coronary arteries. All patients were under 35 
      years of age. Angiographic features for STEMI group were collected and both 
      groups were compared for coronary risk factors. RESULTS: Male sex was more 
      prevalent in acute STEMI group when compared with control participants (83 vs. 
      59%, respectively; P=0.01). A significant difference was found in cigarette 
      smoking (62 vs. 36%, respectively; P=0.007) and family history (33 vs. 16%, 
      respectively; P=0.03) between the two groups. No statistical significance was 
      observed between the groups in terms of hypertension, diabetes mellitus, total 
      cholesterol, low-density lipoprotein cholesterol, and triglyceride levels. Mean 
      high-density lipoprotein cholesterol level was 33+/-8 mg/dl in STEMI group and 
      39+/-12 mg/dl in control participants (P=0.02). Young patients with acute STEMI 
      showed a preponderance of single-vessel disease (69%) and acute anterior STEMI 
      (60%) owing to occluded left anterior descending artery (P<0.001). CONCLUSION: We 
      observed risk factors such as family history, smoking, and low high-density 
      lipoprotein cholesterol levels in young adults. Acute anterior STEMI owing to 
      occluded left anterior descending artery was more frequent. Coronary 
      atherosclerosis was characterized by higher presence of type B and proximal 
      lesions. The handling selection was percutaneous coronary intervention in more 
      than half of the patients.
FAU - Colkesen, Abdurrahman Yucel
AU  - Colkesen AY
AD  - Department of Cardiology, Faculty of Medicine, Baskent University, Ankara, 
      Turkey. kardiyoloji@yahoo.com
FAU - Acil, Tayfun
AU  - Acil T
FAU - Demircan, Senol
AU  - Demircan S
FAU - Sezgin, Alpay T
AU  - Sezgin AT
FAU - Muderrisoglu, Haldun
AU  - Muderrisoglu H
LA  - eng
PT  - Journal Article
PL  - England
TA  - Coron Artery Dis
JT  - Coronary artery disease
JID - 9011445
SB  - IM
MH  - Acute Disease
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Angioplasty, Balloon, Coronary
MH  - Case-Control Studies
MH  - Coronary Angiography/*statistics & numerical data
MH  - Coronary Artery Disease
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Myocardial Infarction/*diagnostic imaging/epidemiology/pathology
MH  - Myocardial Ischemia/diagnostic imaging
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Sex Factors
EDAT- 2008/07/09 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/07/09 09:00
PHST- 2008/07/09 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/07/09 09:00 [entrez]
AID - 00019501-200808000-00009 [pii]
AID - 10.1097/MCA.0b013e3283030b3b [doi]
PST - ppublish
SO  - Coron Artery Dis. 2008 Aug;19(5):345-7. doi: 10.1097/MCA.0b013e3283030b3b.