PMID- 18607679
OWN - NLM
STAT- MEDLINE
DCOM- 20080909
LR  - 20211020
IS  - 1863-6705 (Print)
IS  - 1863-6705 (Linking)
VI  - 56
IP  - 7
DP  - 2008 Jul
TI  - Patient-prosthesis mismatch after aortic valve replacement in the elderly.
PG  - 330-4
LID - 10.1007/s11748-008-0255-6 [doi]
AB  - PURPOSE: The aim of this study was to analyze the effect of patient-prosthesis 
      mismatch (PPM) on survival and left ventricular mass regression in elderly 
      patients after aortic valve replacement (AVR). MATERIALS AND METHODS: Data on 
      patients >65 years old who underwent isolated AVR from 1990 and 2007 were 
      analyzed retrospectively. A bioprosthesis was used in 42 cases and a mechanical 
      valve in 59. The mean follow-up period was 3.1 years (0.1-14.2 years). The 
      indexed effective orifice area (i-EOA) was determined from echocardiographic data 
      in clinical reports in the literature and indexed to body surface area (cm2/m2). 
      Mild PPM was defined as an i-EOA between 0.65 and 0.85. We also evaluated the New 
      York Heart Association (NYHA) classification and the left ventricular mass (LVM) 
      index. RESULTS: A total of 34 patients (33.6%) had PPM. No patient had an i-EOA 
      <0.65. Freedom from valve-related death was 86.3% +/- 6.7% in the PPM-negative 
      group and 85.7% +/- 7.9% in the PPM-positive group at 5 years after AVR. The mean 
      LVM index (g/m2) decreased significantly (P < 0.01), from 239.2 to 167.4 in the 
      PPM-negative group and from 229.1 to 154.4 in the PPM-positive group, 
      respectively. NYHA functional status was excellent at late follow-up in both 
      groups. CONCLUSION: Mild PPM occurred in a large proportion of elderly patients 
      undergoing AVR but did not affect midterm survival or LV mass regression.
FAU - Ryomoto, Masaaki
AU  - Ryomoto M
AD  - Department of Cardiovascular Surgery, Hyogo College of Medicine, 1-1 
      Mukogawa-cho, Nishinomiya, Hyogo, Japan.
FAU - Mitsuno, Masataka
AU  - Mitsuno M
FAU - Yamamura, Mitsuhiro
AU  - Yamamura M
FAU - Tanaka, Hiroe
AU  - Tanaka H
FAU - Kobayashi, Yasuhiko
AU  - Kobayashi Y
FAU - Fukui, Shinya
AU  - Fukui S
FAU - Tsujiya, Noriko
AU  - Tsujiya N
FAU - Kajiyama, Tetsuya
AU  - Kajiyama T
FAU - Miyamoto, Yuji
AU  - Miyamoto Y
LA  - eng
PT  - Journal Article
DEP - 20080708
PL  - Japan
TA  - Gen Thorac Cardiovasc Surg
JT  - General thoracic and cardiovascular surgery
JID - 101303952
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/diagnostic imaging/*surgery
MH  - *Bioprosthesis
MH  - Female
MH  - Heart Valve Diseases/diagnostic imaging/mortality/*surgery
MH  - *Heart Valve Prosthesis
MH  - Heart Valve Prosthesis Implantation/adverse effects/*instrumentation/mortality
MH  - Heart Ventricles/diagnostic imaging
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Prosthesis Design
MH  - Retrospective Studies
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ultrasonography
EDAT- 2008/07/09 09:00
MHDA- 2008/09/10 09:00
CRDT- 2008/07/09 09:00
PHST- 2007/12/05 00:00 [received]
PHST- 2008/03/31 00:00 [accepted]
PHST- 2008/07/09 09:00 [pubmed]
PHST- 2008/09/10 09:00 [medline]
PHST- 2008/07/09 09:00 [entrez]
AID - 10.1007/s11748-008-0255-6 [doi]
PST - ppublish
SO  - Gen Thorac Cardiovasc Surg. 2008 Jul;56(7):330-4. doi: 10.1007/s11748-008-0255-6. 
      Epub 2008 Jul 8.