PMID- 18615388
OWN - NLM
STAT- MEDLINE
DCOM- 20090304
LR  - 20081031
IS  - 0172-4622 (Print)
IS  - 0172-4622 (Linking)
VI  - 29
IP  - 12
DP  - 2008 Dec
TI  - Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of 
      post-exercise cytokine responses.
PG  - 1003-9
LID - 10.1055/s-2008-1038753 [doi]
AB  - Most studies investigating the effects of acute carbohydrate (CHO) ingestion on 
      post-exercise cytokine responses have involved fasted athletes. This study 
      characterised the effects of acute CHO beverage ingestion preceded by consumption 
      of a CHO-containing pre-exercise meal. Sixteen highly-trained male 
      cyclists/triathletes (age: 30.6 +/- 5.6 y; V O (2max): 64.8 +/- 4.7 ml . kg . min 
      (-1) [mean +/- SD]) undertook two cycle ergometry trials involving randomised 
      consumption of a 10 % CHO beverage (15 mL . kg (-1) . hr (-1)) or water (H (2)O). 
      Trials were undertaken 2 h after a breakfast providing 2.1 g CHO . kg (-1) body 
      mass (BM) (48 kJ . kg (-1) BM) and consisted of 100 min steady state cycle 
      ergometry at 70 % V O (2max) followed by a time trial of approximately 30 min 
      duration. Blood samples were collected pre-, post- and 1 h post-exercise for 
      measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance 
      was not substantially different between CHO and H (2)O trials (4.5 %, p = 0.42). 
      Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to 
      the H (2)O trial. There was a substantial reduction in IL-10 (32 %, p = 0.05) and 
      IL-1ra (43 %, p = 0.02) responses at 1 h post-exercise with CHO compared to H 
      (2)O ingestion. In conclusion, the previously shown attenuating effects of CHO 
      ingestion during exercise on cytokine responses appear reduced when athletes 
      consume a CHO-containing pre-exercise meal.
FAU - Cox, A J
AU  - Cox AJ
AD  - Department of Physiology, Australian Institute of Sport, Belconnen, Australia. 
      amanda.cox@newcastle.edu.au
FAU - Pyne, D B
AU  - Pyne DB
FAU - Cox, G R
AU  - Cox GR
FAU - Callister, R
AU  - Callister R
FAU - Gleeson, M
AU  - Gleeson M
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20080709
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Blood Glucose)
RN  - 0 (Cytokines)
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - Adult
MH  - Bicycling/*physiology
MH  - Blood Glucose
MH  - *Cytokines
MH  - Dietary Carbohydrates/*metabolism
MH  - *Energy Metabolism
MH  - Ergometry/instrumentation
MH  - Exercise/*physiology
MH  - Exercise Test
MH  - Humans
MH  - Male
MH  - *Nutritional Status
MH  - Oxygen Consumption
MH  - Time Factors
EDAT- 2008/07/11 09:00
MHDA- 2009/03/05 09:00
CRDT- 2008/07/11 09:00
PHST- 2008/07/11 09:00 [pubmed]
PHST- 2009/03/05 09:00 [medline]
PHST- 2008/07/11 09:00 [entrez]
AID - 10.1055/s-2008-1038753 [doi]
PST - ppublish
SO  - Int J Sports Med. 2008 Dec;29(12):1003-9. doi: 10.1055/s-2008-1038753. Epub 2008 
      Jul 9.