PMID- 18628585
OWN - NLM
STAT- MEDLINE
DCOM- 20081003
LR  - 20190606
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 47
IP  - 14
DP  - 2008
TI  - Probable cerebral Mycobacterium avium complex-related immune reconstitution 
      inflammatory syndrome in an HIV-infected patient.
PG  - 1349-54
AB  - The advent of highly active anti-retroviral therapy (HAART) has reduced both the 
      morbidity and incidence of acquired immunodeficiency syndrome (AIDS)-related 
      central nervous system (CNS) diseases. However, some patients seem to suffer 
      paradoxical clinical deterioration after starting HAART, known as immune 
      reconstitution inflammatory syndrome (IRIS). We report a rare case of probable 
      Mycobacterium avium complex (MAC) infection of the brain in a patient with AIDS 
      who had been treated effectively for probable pulmonary and cerebral MAC 
      infection, with both lesions recurring after significant decreases in plasma 
      human immunodeficiency virus type-1 viral load following initiation of HAART. 
      This case appears to represent the first precise clinicopathological description 
      of severe ventriculo-encephalitis in CNS MAC-related IRIS.
FAU - Kishida, Shuji
AU  - Kishida S
AD  - Division of Neurology, Tokyo Metropolitan Cancer and Infectious Diseases Center, 
      Komagome Hospital, Tokyo. s-kisida@cick.jp
FAU - Ajisawa, Atsushi
AU  - Ajisawa A
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20080715
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
MH  - AIDS-Related Opportunistic Infections/microbiology/*pathology
MH  - Antiretroviral Therapy, Highly Active/adverse effects
MH  - Central Nervous System Bacterial Infections/diagnosis/*pathology
MH  - Cerebral Ventricles/microbiology/*pathology
MH  - Fatal Outcome
MH  - HIV Infections/*complications
MH  - *HIV-1
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*complications
MH  - Male
MH  - Middle Aged
MH  - Mycobacterium avium-intracellulare Infection/*pathology
EDAT- 2008/07/17 09:00
MHDA- 2008/10/04 09:00
CRDT- 2008/07/17 09:00
PHST- 2008/07/17 09:00 [pubmed]
PHST- 2008/10/04 09:00 [medline]
PHST- 2008/07/17 09:00 [entrez]
AID - JST.JSTAGE/internalmedicine/47.0893 [pii]
AID - 10.2169/internalmedicine.47.0893 [doi]
PST - ppublish
SO  - Intern Med. 2008;47(14):1349-54. doi: 10.2169/internalmedicine.47.0893. Epub 2008 
      Jul 15.