PMID- 18633208
OWN - NLM
STAT- MEDLINE
DCOM- 20080911
LR  - 20191111
IS  - 0015-6426 (Print)
IS  - 0015-6426 (Linking)
VI  - 49
IP  - 3
DP  - 2008 Jun
TI  - Multiresidue method for pesticides and veterinary drugs in bovine milk using 
      GC/MS and LC/MS/MS.
PG  - 228-38
AB  - A simple, sensitive and selective method with gas chromatography/mass 
      spectrometry (GC/MS) and liquid chromatography/tandem mass spectrometry 
      (LC/MS/MS) has been developed to detect 342 pesticides and veterinary drugs 
      contaminating bovine milk at the maximum residue limits (MRLs) defined in the 
      "positive list system". Sample preparation was performed by extracting the 
      analytes with acetonitrile, followed by salting-out with sodium chloride. For 
      some pesticides, the extract was further cleaned up by n-hexane partitioning and 
      PSA cartridge column chromatography. GC/MS-EI or -NCI was used to determine 
      pesticide residues, while LC/MS/MS-ESI was applicable to the determination of 
      pesticide and veterinary drug residues. The variation of the recoveries of these 
      drugs at MRL was relatively wide; however the relative standard deviations of the 
      recovery of each drug were within 28%, suggesting that the present method is good 
      enough for use as a screening test for contaminants at the MRLs. These results 
      show that this method is useful for multiresidue analysis of numerous pesticides 
      and veterinary drugs in bovine milk.
FAU - Saito, Mizue
AU  - Saito M
AD  - Analysis and Food Hygiene Department, Food Technology Research Institute, Meiji 
      Dairies Corporation, Kanagawa, Japan.
FAU - Kozutsumi, Daisuke
AU  - Kozutsumi D
FAU - Kawasaki, Michiko
AU  - Kawasaki M
FAU - Kanbashi, Miho
AU  - Kanbashi M
FAU - Nakamura, Ruka
AU  - Nakamura R
FAU - Sato, Yoshio
AU  - Sato Y
FAU - Endo, Mitsuharu
AU  - Endo M
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Shokuhin Eiseigaku Zasshi
JT  - Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan
JID - 0142214
RN  - 0 (Pesticide Residues)
RN  - 0 (Veterinary Drugs)
SB  - IM
MH  - Animals
MH  - Cattle
MH  - Female
MH  - *Gas Chromatography-Mass Spectrometry
MH  - Milk/*chemistry
MH  - Pesticide Residues/*analysis
MH  - *Tandem Mass Spectrometry
MH  - Veterinary Drugs/*analysis
EDAT- 2008/07/18 09:00
MHDA- 2008/09/13 09:00
CRDT- 2008/07/18 09:00
PHST- 2008/07/18 09:00 [pubmed]
PHST- 2008/09/13 09:00 [medline]
PHST- 2008/07/18 09:00 [entrez]
AID - JST.JSTAGE/shokueishi/49.228 [pii]
AID - 10.3358/shokueishi.49.228 [doi]
PST - ppublish
SO  - Shokuhin Eiseigaku Zasshi. 2008 Jun;49(3):228-38. doi: 10.3358/shokueishi.49.228.