PMID- 18636217
OWN - NLM
STAT- MEDLINE
DCOM- 20100202
LR  - 20211020
IS  - 1433-2965 (Electronic)
IS  - 0937-941X (Linking)
VI  - 20
IP  - 3
DP  - 2009 Mar
TI  - Geographical variations in hip fracture risk for women: strong effects hidden in 
      standardised ratios.
PG  - 371-7
LID - 10.1007/s00198-008-0687-y [doi]
AB  - There was 75% variation in the trend in hip fracture incidence with age in women 
      aged 50 to 85 in France. In southwest France, the women are at higher risk of hip 
      fracture at younger ages. This finding should be taken into account when 
      examining risk factors. INTRODUCTION: Few studies have analysed the geographical 
      variations in the relationship between age and hip fracture incidence. Our goal 
      was to assess these variations among women under 85 within the same country. 
      METHODS: The study population included women aged 50 to 85 who were living in 
      France in 2004. Hip fracture cases were identified in the French Diagnosis 
      Related Groups (DRG)-like database using the diagnosis code for closed hip 
      fractures and procedural codes for treatment. The Moran index and a spatial model 
      using latitude and longitude were used to assess the geographical heterogeneities 
      of cumulative incidence risk (CIR) and age effect. RESULTS: A total of 29,218 hip 
      fracture cases were identified. A south-to-north CIR gradient ranging from 7 to 
      16% was observed. The variation in the number of years until double hip fracture 
      incidence was 75% (i.e. 1.49 to 2.57 years). In the south, and more markedly in 
      southwest France, the women are at higher risk of hip fracture at a younger age. 
      CONCLUSION: The risk of fracture may be different between women of the same age. 
      This may be hidden in a comparison of standardised ratios. This finding should be 
      considered when examining risk factors and implementing public health 
      interventions.
FAU - Barbier, S
AU  - Barbier S
AD  - Service de Biostatistique, Hospices Civils de Lyon, Lyon, 69003, France.
FAU - Ecochard, R
AU  - Ecochard R
FAU - Schott, A-M
AU  - Schott AM
FAU - Colin, C
AU  - Colin C
FAU - Delmas, P D
AU  - Delmas PD
FAU - Jaglal, S B
AU  - Jaglal SB
FAU - Couris, C M
AU  - Couris CM
LA  - eng
PT  - Journal Article
DEP - 20080718
PL  - England
TA  - Osteoporos Int
JT  - Osteoporosis international : a journal established as result of cooperation 
      between the European Foundation for Osteoporosis and the National Osteoporosis 
      Foundation of the USA
JID - 9100105
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - France/epidemiology
MH  - Hip Fractures/*epidemiology
MH  - Humans
MH  - Incidence
MH  - Middle Aged
MH  - Population Surveillance/methods
MH  - Reference Values
MH  - Risk Factors
EDAT- 2008/07/19 09:00
MHDA- 2010/02/03 06:00
CRDT- 2008/07/19 09:00
PHST- 2008/03/04 00:00 [received]
PHST- 2008/06/03 00:00 [accepted]
PHST- 2008/07/19 09:00 [pubmed]
PHST- 2010/02/03 06:00 [medline]
PHST- 2008/07/19 09:00 [entrez]
AID - 10.1007/s00198-008-0687-y [doi]
PST - ppublish
SO  - Osteoporos Int. 2009 Mar;20(3):371-7. doi: 10.1007/s00198-008-0687-y. Epub 2008 
      Jul 18.