PMID- 18641722
OWN - NLM
STAT- MEDLINE
DCOM- 20081231
LR  - 20160513
IS  - 1715-5312 (Print)
IS  - 1715-5312 (Linking)
VI  - 33
IP  - 4
DP  - 2008 Aug
TI  - Acute milk-based protein-CHO supplementation attenuates exercise-induced muscle 
      damage.
PG  - 775-83
LID - 10.1139/H08-057 [doi]
AB  - Exercise-induced muscle damage (EIMD) leads to the degradation of protein 
      structures within the muscle. This may subsequently lead to decrements in muscle 
      performance and increases in intramuscular enzymes and delayed-onset muscle 
      soreness (DOMS). Milk, which provides protein and carbohydrate (CHO), may lead to 
      the attenuation of protein degradation and (or) an increase in protein synthesis 
      that would limit the consequential effects of EIMD. This study examined the 
      effects of acute milk and milk-based protein-CHO (CHO-P) supplementation on 
      attenuating EIMD. Four independent groups of 6 healthy males consumed water 
      (CON), CHO sports drink, milk-based CHO-P or milk (M), post EIMD. DOMS, 
      isokinetic muscle performance, creatine kinase (CK), and myoglobin (Mb) were 
      assessed immediately before and 24 and 48 h after EIMD. DOMS was not 
      significantly different (p > 0.05) between groups at any time point. Peak torque 
      (dominant) was significantly higher (p < 0.05) 48 h after CHO-P compared with CHO 
      and CON, and M compared with CHO. Total work of the set (dominant) was 
      significantly higher (p < 0.05) 48 h after CHO-P and M compared with CHO and CON. 
      CK was significantly lower (p < 0.05) 48 h after CHO-P and M compared with CHO. 
      Mb was significantly lower (p < 0.05) 48 h after CHO-P compared with CHO. At 48 h 
      post-EIMD, milk and milk-based protein-CHO supplementation resulted in the 
      attenuation of decreases in isokinetic muscle performance and increases in CK and 
      Mb.
FAU - Cockburn, Emma
AU  - Cockburn E
AD  - Division of Sports Sciences, Northumbria University, Newcastle, UK. 
      e.cockburn@unn.ac.uk
FAU - Hayes, Philip R
AU  - Hayes PR
FAU - French, Duncan N
AU  - French DN
FAU - Stevenson, Emma
AU  - Stevenson E
FAU - St Clair Gibson, Alan
AU  - St Clair Gibson A
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - Canada
TA  - Appl Physiol Nutr Metab
JT  - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition 
      et metabolisme
JID - 101264333
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Myoglobin)
RN  - 059QF0KO0R (Water)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Animals
MH  - Athletic Injuries/prevention & control
MH  - Beverages
MH  - Creatine Kinase/blood
MH  - Dietary Carbohydrates/administration & dosage/*therapeutic use
MH  - Dietary Proteins/administration & dosage/*therapeutic use
MH  - Dietary Supplements/*statistics & numerical data
MH  - *Exercise
MH  - Humans
MH  - Kinetics
MH  - Male
MH  - *Milk
MH  - Muscle, Skeletal/*injuries/metabolism
MH  - Myoglobin/blood
MH  - Reference Values
MH  - Single-Blind Method
MH  - Sports
MH  - Time Factors
MH  - Water/administration & dosage
MH  - Young Adult
EDAT- 2008/07/22 09:00
MHDA- 2009/01/01 09:00
CRDT- 2008/07/22 09:00
PHST- 2008/07/22 09:00 [pubmed]
PHST- 2009/01/01 09:00 [medline]
PHST- 2008/07/22 09:00 [entrez]
AID - h08-057 [pii]
AID - 10.1139/H08-057 [doi]
PST - ppublish
SO  - Appl Physiol Nutr Metab. 2008 Aug;33(4):775-83. doi: 10.1139/H08-057.