PMID- 18658234
OWN - NLM
STAT- MEDLINE
DCOM- 20090403
LR  - 20220331
IS  - 1469-445X (Electronic)
IS  - 0958-0670 (Linking)
VI  - 94
IP  - 1
DP  - 2009 Jan
TI  - Effects of low-frequency whole-body vibration on motor-evoked potentials in 
      healthy men.
PG  - 103-16
LID - 10.1113/expphysiol.2008.042689 [doi]
AB  - The aim of this study was to determine whether low-frequency whole-body vibration 
      (WBV) modulates the excitability of the corticospinal and intracortical pathways 
      related to tibialis anterior (TA) muscle activity, thus contributing to the 
      observed changes in neuromuscular function during and after WBV exercise. 
      Motor-evoked potentials (MEPs) elicited in response to transcranial magnetic 
      stimulation (TMS) of the leg area of the motor cortex were recorded in TA and 
      soleus (SOL) muscles of seven healthy male subjects whilst performing 330 s 
      continuous static squat exercise. Each subject completed two conditions: control 
      (no WBV) and WBV (30 Hz, 1.5 mm vibration applied from 111 to 220 s). Five single 
      suprathreshold and five paired TMS were delivered during each squat period 
      lasting 110 s (pre-, during and post-WBV). Two interstimulus intervals (ISIs) 
      between the conditioning and the testing stimuli were employed in order to study 
      the effects of WBV on short-interval intracortical inhibition (SICI, ISI = 3 ms) 
      and intracortical facilitation (ICF, ISI = 13 ms). During vibration relative to 
      squat exercise alone, single-pulse TMS provoked significantly higher TA MEP 
      amplitude (56 +/- 14%, P = 0.003) and total area (71 +/- 19%, P = 0.04), and 
      paired TMS with ISI = 13 ms provoked smaller MEP amplitude (-21 +/- 4%, P = 0.01) 
      but not in SOL. Paired-pulse TMS with ISI = 3 ms elicited significantly lower MEP 
      amplitude (TA, -19 +/- 4%, P = 0.009; and SOL, -13 +/- 4%, P = 0.03) and total 
      area (SOL, -17 +/- 6%, P = 0.02) during vibration relative to squat exercise 
      alone in both muscles. Tibialis anterior MEP facilitation in response to 
      single-pulse TMS suggests that WBV increased corticospinal pathway excitability. 
      Increased TA and SOL SICI and decreased TA ICF in response to paired-pulse TMS 
      during WBV indicate vibration-induced alteration of the intracortical processes 
      as well.
FAU - Mileva, Katya N
AU  - Mileva KN
AD  - Sport and Exercise Science Research Centre, Faculty of Engineering, Science and 
      The Built Environment, London South Bank University, 103 Borough Road, London SE1 
      0AA, UK. milevakn@lsbu.ac.uk
FAU - Bowtell, Joanna L
AU  - Bowtell JL
FAU - Kossev, Andon R
AU  - Kossev AR
LA  - eng
PT  - Journal Article
DEP - 20080725
PL  - England
TA  - Exp Physiol
JT  - Experimental physiology
JID - 9002940
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Electromyography
MH  - Evoked Potentials, Motor/*physiology
MH  - Exercise/*physiology
MH  - Humans
MH  - Leg/innervation
MH  - Male
MH  - Middle Aged
MH  - Motor Cortex/*physiology
MH  - Muscle Contraction/physiology
MH  - Muscle, Skeletal/innervation/physiology
MH  - Neuronal Plasticity/physiology
MH  - Pyramidal Tracts/*physiology
MH  - Transcranial Magnetic Stimulation
MH  - *Vibration
EDAT- 2008/07/29 09:00
MHDA- 2009/04/04 09:00
CRDT- 2008/07/29 09:00
PHST- 2008/07/29 09:00 [pubmed]
PHST- 2009/04/04 09:00 [medline]
PHST- 2008/07/29 09:00 [entrez]
AID - expphysiol.2008.042689 [pii]
AID - 10.1113/expphysiol.2008.042689 [doi]
PST - ppublish
SO  - Exp Physiol. 2009 Jan;94(1):103-16. doi: 10.1113/expphysiol.2008.042689. Epub 
      2008 Jul 25.