PMID- 18664991
OWN - NLM
STAT- MEDLINE
DCOM- 20090413
LR  - 20131121
IS  - 1536-7355 (Electronic)
IS  - 1076-1608 (Linking)
VI  - 14
IP  - 6
DP  - 2008 Dec
TI  - Subacute cutaneous lupus erythematosus and interstitial myositis occurring with 
      hepatitis B infection: response to antiviral therapy with lamivudine.
PG  - 346-9
LID - 10.1097/RHU.0b013e31817de0e7 [doi]
AB  - Lupus erythematosus (LE) is a multisystem inflammatory disease resulting from an 
      altered T- and B-cell response. Among various pathogenic factors, viral 
      infections have been implicated in LE exacerbation. We describe a patient with 
      acute onset of subacute cutaneous lupus erythematosus (SCLE) and interstitial 
      myositis with mitochondrial changes in the context of an associated hepatitis B 
      infection and the response of myositis to antiviral treatment with lamivudine. 
      Viral vectors may play an important role in LE. A hitherto undescribed myositis 
      with mitochondrial changes was associated with hepatitis B infection and SCLE and 
      improved with antiviral treatment.
FAU - Gruber-Wackernagel, Alexandra
AU  - Gruber-Wackernagel A
AD  - Department of Dermatology, Medical University Graz, Graz, Austria.
FAU - Scarpatetti, Michael
AU  - Scarpatetti M
FAU - Gruber, Martin Jochen
AU  - Gruber MJ
FAU - Hermann, Josef
AU  - Hermann J
FAU - Aberer, Elisabeth
AU  - Aberer E
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Clin Rheumatol
JT  - Journal of clinical rheumatology : practical reports on rheumatic & 
      musculoskeletal diseases
JID - 9518034
RN  - 0 (Antiviral Agents)
RN  - 2T8Q726O95 (Lamivudine)
SB  - IM
MH  - Aged
MH  - Antiviral Agents/*therapeutic use
MH  - Female
MH  - Hepatitis B/*complications/*drug therapy
MH  - Humans
MH  - Lamivudine/*therapeutic use
MH  - Lupus Erythematosus, Cutaneous/diagnosis/drug therapy/*virology
MH  - Mitochondria/pathology
MH  - Myositis/diagnosis/drug therapy/*virology
MH  - Skin/pathology
MH  - Treatment Outcome
EDAT- 2008/07/31 09:00
MHDA- 2009/04/14 09:00
CRDT- 2008/07/31 09:00
PHST- 2008/07/31 09:00 [pubmed]
PHST- 2009/04/14 09:00 [medline]
PHST- 2008/07/31 09:00 [entrez]
AID - 10.1097/RHU.0b013e31817de0e7 [doi]
PST - ppublish
SO  - J Clin Rheumatol. 2008 Dec;14(6):346-9. doi: 10.1097/RHU.0b013e31817de0e7.