PMID- 18666099 OWN - NLM STAT- MEDLINE DCOM- 20081114 LR - 20211020 IS - 1522-2594 (Electronic) IS - 0740-3194 (Print) IS - 0740-3194 (Linking) VI - 60 IP - 2 DP - 2008 Aug TI - Simulation of relative temporal resolution of time-resolved MRA sequences. PG - 398-404 LID - 10.1002/mrm.21658 [doi] AB - Time-resolved MRA sequences are typically characterized by the display frame rate. However, true temporal resolution should be defined in a manner analogous to spatial resolution; it is not the ability of a sequence to update rapidly but rather the ability to discern changes that occur within a small time that should characterize temporal resolution. For view-shared methods like Keyhole and time-resolved imaging of contrast kinetics (TRICKS), regions of k-space from multiple time frames are combined to form a single reconstructed time frame. This often causes the time needed to acquire all k-space data points to be significantly longer than the displayed frame time, resulting in a poor frequency response. Simulated here are the temporal impulse response and temporal frequency response (TFR) curves of three time-resolved MRA methods, including the recently introduced highly-constrained backprojection local reconstruction (HYPR LR) method. It is found that the HYPR LR reconstruction method exhibits a better TFR for a larger spectrum of temporal and spatial frequencies than the Keyhole and TRICKS methods. CI - (c) 2008 Wiley-Liss, Inc. FAU - Keith, L AU - Keith L AD - Department of Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA. keith@wisc.edu FAU - Kecskemeti, S AU - Kecskemeti S FAU - Velikina, J AU - Velikina J FAU - Mistretta, C AU - Mistretta C LA - eng GR - R01 HL072260/HL/NHLBI NIH HHS/United States GR - R01 HL072260-01/HL/NHLBI NIH HHS/United States GR - 1R01HL72260-01/HL/NHLBI NIH HHS/United States PT - Evaluation Study PT - Journal Article PT - Research Support, N.I.H., Extramural PL - United States TA - Magn Reson Med JT - Magnetic resonance in medicine JID - 8505245 SB - IM MH - *Algorithms MH - Computer Simulation MH - Humans MH - Image Enhancement/methods MH - Image Interpretation, Computer-Assisted/*methods MH - Magnetic Resonance Angiography/*methods MH - *Models, Cardiovascular MH - *Models, Neurological MH - Reproducibility of Results MH - Sensitivity and Specificity PMC - PMC2613762 MID - NIHMS64984 EDAT- 2008/07/31 09:00 MHDA- 2008/11/15 09:00 PMCR- 2009/08/01 CRDT- 2008/07/31 09:00 PHST- 2008/07/31 09:00 [pubmed] PHST- 2008/11/15 09:00 [medline] PHST- 2008/07/31 09:00 [entrez] PHST- 2009/08/01 00:00 [pmc-release] AID - 10.1002/mrm.21658 [doi] PST - ppublish SO - Magn Reson Med. 2008 Aug;60(2):398-404. doi: 10.1002/mrm.21658.