PMID- 18669025
OWN - NLM
STAT- MEDLINE
DCOM- 20080826
LR  - 20240109
IS  - 0939-5075 (Print)
IS  - 0341-0382 (Linking)
VI  - 63
IP  - 5-6
DP  - 2008 May-Jun
TI  - Chemical basis for the phytotoxicity of N-aryl hydroxamic acids and acetanilide 
      analogues.
PG  - 389-94
AB  - Germination inhibition activity of N-aryl hydroxamic acids and acetanilide 
      analogues was measured on lettuce seeds (Lactuca sativa). Lipophilicity of the 
      compounds was determined by HPLC. A correlation between lipophilicity values and 
      percentage of germination inhibition was established. A model mechanism of action 
      for auxin was used for analyzing the effect of the substituent at the alpha 
      carbon atom (Ca) on the polarization of hydroxamic and amide functions in 
      relation to the germination inhibition activity observed. Results suggest that 
      the lipophilic and acidic properties play an important role in the phytotoxicity 
      of the compounds. A test with the microalga Chlorella vulgaris was used to 
      evaluate the potential herbicide activity of the hydroxamic acids and 
      acetanilides.
FAU - Bravo, Hector R
AU  - Bravo HR
AD  - Departamento de Quimica, Facultad de Ciencias, Universidad de Chile, Casilla 653, 
      Santiago, Chile.
FAU - Villarroel, Elisa
AU  - Villarroel E
FAU - Copaja, Sylvia V
AU  - Copaja SV
FAU - Argandona, Victor H
AU  - Argandona VH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Z Naturforsch C J Biosci
JT  - Zeitschrift fur Naturforschung. C, Journal of biosciences
JID - 8912155
RN  - 0 (Acetanilides)
RN  - 0 (Hydroxamic Acids)
SB  - IM
MH  - Acetanilides/*chemistry/*pharmacology
MH  - Chlorella/*drug effects
MH  - Hydroxamic Acids/*chemistry/*pharmacology
MH  - Lactuca/drug effects
MH  - Seeds/drug effects
EDAT- 2008/08/02 09:00
MHDA- 2008/08/30 09:00
CRDT- 2008/08/02 09:00
PHST- 2008/08/02 09:00 [pubmed]
PHST- 2008/08/30 09:00 [medline]
PHST- 2008/08/02 09:00 [entrez]
AID - 10.1515/znc-2008-5-613 [doi]
PST - ppublish
SO  - Z Naturforsch C J Biosci. 2008 May-Jun;63(5-6):389-94. doi: 
      10.1515/znc-2008-5-613.