PMID- 18669226 OWN - NLM STAT- MEDLINE DCOM- 20080909 LR - 20181201 IS - 0350-199X (Linking) VI - 62 IP - 2 DP - 2008 TI - Statistical evaluation of olanzapine efficacy in catamnesticly investigated patients. PG - 85-7 AB - The aims of this research are: a) To compare GAF (Global Assessment of Functioning) score after the olanzapine treatment with the GAF score recorded after the treatment conducted by typical antipsychotics; b) To compare CGI (Global Clinical Impression) score after the treatment with CGI subsequent to treatment by typical antipsychotics; c) To compare number of hospitalizations of patients during the treatment with olanzapine with the number of hospitalizations during previous treatment; and 4. To monitor and record the possible weight gain of patients who were taking olanzapine. The research was conducted in the period from 2004 to 2007 in the Department of Psychiatry of the University Clinical Center in Sarajevo. Research subjects were patients with diagnosed schizophrenia who did not have expected response to the treatment with conventional antipsychotics, or who experienced serious adverse effects in the course of this treatment. Daily dosage of olanzapine was adjusted to the clinical condition of the patient and it varied from 5 to 20 mg a day. Clinical assessment is done once a month with CGI scale and GAF scale. During follow-up the possible weight gain was also followed. Statistically significant difference was found (p<0.001). FAU - Skrbo, Armin AU - Skrbo A AD - Faculty of pharmacy, University of Sarajevo. FAU - Djedjibegovic, Jasmina AU - Djedjibegovic J FAU - Jovanovic-Gmaz, Mirjana AU - Jovanovic-Gmaz M FAU - Kapetanovic, Diana AU - Kapetanovic D FAU - Sahovic, Dzenana AU - Sahovic D FAU - Todorovic, Ljubica AU - Todorovic L LA - eng PT - Journal Article PL - Bosnia and Herzegovina TA - Med Arh JT - Medicinski arhiv JID - 0400722 RN - 0 (Antipsychotic Agents) RN - 12794-10-4 (Benzodiazepines) RN - N7U69T4SZR (Olanzapine) SB - IM MH - Antipsychotic Agents/adverse effects/*therapeutic use MH - Benzodiazepines/adverse effects/*therapeutic use MH - Female MH - Hospitalization MH - Humans MH - Male MH - Olanzapine MH - Schizophrenia/*drug therapy EDAT- 2008/08/02 09:00 MHDA- 2008/09/10 09:00 CRDT- 2008/08/02 09:00 PHST- 2008/08/02 09:00 [pubmed] PHST- 2008/09/10 09:00 [medline] PHST- 2008/08/02 09:00 [entrez] PST - ppublish SO - Med Arh. 2008;62(2):85-7.