PMID- 18684415
OWN - NLM
STAT- MEDLINE
DCOM- 20081231
LR  - 20121017
IS  - 1878-0210 (Electronic)
IS  - 1878-0210 (Linking)
VI  - 2
IP  - 1
DP  - 2008 Feb
TI  - Initiating insulin in primary care--the role of modern premixed formulations.
PG  - 9-16
LID - 10.1016/j.pcd.2008.01.005 [doi]
AB  - Starting insulin therapy earlier can help reduce the risk of micro- and 
      macrovascular complications associated with the progression of type 2 diabetes 
      mellitus (T2DM). However, barriers to the initiation of insulin have been 
      identified. Premixed insulins offer a simpler regimen than basal-bolus therapy 
      for T2DM. Modern premixes, which combine a rapid-acting soluble insulin with a 
      protaminated form of the same insulin, have become increasingly popular. As 
      primary care practitioners and diabetes specialists are encouraged to initiate 
      insulin, premixes that can be used within flexible dosing regimens to improve 
      glycaemic control could be beneficial.
FAU - Ligthelm, Robert
AU  - Ligthelm R
AD  - EHM Clinic Hoofddorp's-Gravenweg 53, Rotterdam 3062 ZB, The Netherlands. 
      rjligthe@xs4all.nl
FAU - Davidson, Jaime
AU  - Davidson J
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Prim Care Diabetes
JT  - Primary care diabetes
JID - 101463825
RN  - 0 (Drug Combinations)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
SB  - IM
MH  - Diabetes Complications/*prevention & control
MH  - Diabetes Mellitus, Type 2/*drug therapy
MH  - Drug Combinations
MH  - Humans
MH  - Hypoglycemic Agents/*therapeutic use
MH  - Insulin/*therapeutic use
MH  - *Primary Health Care
MH  - Treatment Outcome
RF  - 63
EDAT- 2008/08/08 09:00
MHDA- 2009/01/01 09:00
CRDT- 2008/08/08 09:00
PHST- 2007/10/08 00:00 [received]
PHST- 2007/12/11 00:00 [revised]
PHST- 2008/01/08 00:00 [accepted]
PHST- 2008/08/08 09:00 [pubmed]
PHST- 2009/01/01 09:00 [medline]
PHST- 2008/08/08 09:00 [entrez]
AID - S1751-9918(08)00003-X [pii]
AID - 10.1016/j.pcd.2008.01.005 [doi]
PST - ppublish
SO  - Prim Care Diabetes. 2008 Feb;2(1):9-16. doi: 10.1016/j.pcd.2008.01.005.