PMID- 18684529
OWN - NLM
STAT- MEDLINE
DCOM- 20100413
LR  - 20151119
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 138
IP  - 2
DP  - 2010 Jan 21
TI  - Uric acid in the acute phase of ST elevation myocardial infarction submitted to 
      primary PCI: its prognostic role and relation with inflammatory markers: a single 
      center experience.
PG  - 206-9
LID - 10.1016/j.ijcard.2008.06.024 [doi]
AB  - BACKGROUND AND METHODS: Scarce data are available on the prognostic role of uric 
      acid (UA ) in patients with ST elevation myocardial infarction (STEMI). We aimed 
      at assessing the relation between uric acid, measured on Intensive Cardiac Care 
      Unit (ICCU) admission, and mortality at short term follow-up in 466 consecutive 
      STEMI patients submitted to percutaneous coronary intervention (PCI), as well as 
      its relation with inflammatory markers (C-reactive protein, CRP-fibrinogen, 
      erythrocyte sedimentation rate ESR). RESULTS: Higher UA were detectable in the 
      21.5%.. In-hospital mortality was higher in patients with elevated UA (p<0.01 
      O.R. (95% C.I.): 3.9 (1.5-10.2)). At backward stepwise regression analysis UA 
      resulted an independent predictor for in-hospital mortality (OR 1.82, 95%CI 
      1.15-2.86; p=0.01). CONCLUSION: Our data strongly suggest that in the acute phase 
      of STEMI patients submitted to PCI, uric acid holds a prognostic role for 
      in-hospital mortality.
CI  - Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved.
FAU - Lazzeri, Chiara
AU  - Lazzeri C
FAU - Valente, Serafina
AU  - Valente S
FAU - Chiostri, Marco
AU  - Chiostri M
FAU - Sori, Andrea
AU  - Sori A
FAU - Bernardo, Pasquale
AU  - Bernardo P
FAU - Gensini, Gian Franco
AU  - Gensini GF
LA  - eng
PT  - Comment
PT  - Letter
DEP - 20080805
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
RN  - 0 (Biomarkers)
RN  - 268B43MJ25 (Uric Acid)
SB  - IM
CON - Int J Cardiol. 2008 Apr 10;125(2):232-9. PMID: 18237790
CIN - Int J Cardiol. 2010 Nov 5;145(1):e21-2. PMID: 19157598
MH  - Aged
MH  - Biomarkers/*blood
MH  - *Critical Care
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Infarction/blood/immunology/mortality
MH  - Prognosis
MH  - Uric Acid/*blood
EDAT- 2008/08/08 09:00
MHDA- 2010/04/14 06:00
CRDT- 2008/08/08 09:00
PHST- 2008/03/30 00:00 [received]
PHST- 2008/06/07 00:00 [accepted]
PHST- 2008/08/08 09:00 [pubmed]
PHST- 2010/04/14 06:00 [medline]
PHST- 2008/08/08 09:00 [entrez]
AID - S0167-5273(08)00794-8 [pii]
AID - 10.1016/j.ijcard.2008.06.024 [doi]
PST - ppublish
SO  - Int J Cardiol. 2010 Jan 21;138(2):206-9. doi: 10.1016/j.ijcard.2008.06.024. Epub 
      2008 Aug 5.