PMID- 18684531 OWN - NLM STAT- MEDLINE DCOM- 20091021 LR - 20090804 IS - 1874-1754 (Electronic) IS - 0167-5273 (Linking) VI - 136 IP - 3 DP - 2009 Aug 21 TI - Monocyte chemoattractant protein-1 in acute coronary syndromes: complex vicious interaction. PG - 356-7 LID - 10.1016/j.ijcard.2008.04.080 [doi] AB - Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role both in the initiation and progression of atherosclerosis. MCP-1 is a unique cytokine produced by macrophages, smooth muscle cells and endothelial cells within atherosclerotic plaques and seems to be a reliable indicator of atherosclerotic plaque burden. Higher levels of MCP-1 have been associated with a poor prognosis and increased risk for death independent of other risk factors in patients with acute coronary syndromes. In this paper, we discussed the role of MCP-1 in the pathogenesis of acute coronary syndromes. FAU - Amasyali, Basri AU - Amasyali B AD - Gulhane Military Medical School, Department of Cardiology, Etlik/Ankara, Turkey. dramasyali@yahoo.com FAU - Kose, Sedat AU - Kose S FAU - Kursaklioglu, Hurkan AU - Kursaklioglu H FAU - Barcin, Cem AU - Barcin C FAU - Kilic, Ayhan AU - Kilic A LA - eng PT - Letter DEP - 20080805 PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 RN - 0 (Chemokine CCL2) SB - IM MH - Acute Coronary Syndrome/*epidemiology/*immunology MH - Atherosclerosis/*epidemiology/*immunology MH - Chemokine CCL2/blood/*immunology MH - Humans MH - Risk Factors EDAT- 2008/08/08 09:00 MHDA- 2009/10/22 06:00 CRDT- 2008/08/08 09:00 PHST- 2008/01/11 00:00 [received] PHST- 2008/04/26 00:00 [accepted] PHST- 2008/08/08 09:00 [pubmed] PHST- 2009/10/22 06:00 [medline] PHST- 2008/08/08 09:00 [entrez] AID - S0167-5273(08)00671-2 [pii] AID - 10.1016/j.ijcard.2008.04.080 [doi] PST - ppublish SO - Int J Cardiol. 2009 Aug 21;136(3):356-7. doi: 10.1016/j.ijcard.2008.04.080. Epub 2008 Aug 5.