PMID- 18694742
OWN - NLM
STAT- MEDLINE
DCOM- 20090417
LR  - 20080915
IS  - 0009-8981 (Print)
IS  - 0009-8981 (Linking)
VI  - 397
IP  - 1-2
DP  - 2008 Nov
TI  - The determination of persistent organic pollutants (POPs) in the colostrums of 
      women in preterm labor.
PG  - 18-21
LID - 10.1016/j.cca.2008.07.004 [doi]
AB  - BACKGROUND: Human milk not only contains nutrients and antibodies, but also can 
      be used as an indicator for levels of organic pollutants in human bodies. We 
      developed a method for determining persistent organic pollutants (POPs) in the 
      colostrum of women in preterm labor, the POPs of 36 colostrum samples have been 
      examined. METHODS: Thirty-six samples of colostrum from preterm women were 
      extracted by acetone-acetonitrile, enriched and purified by solid-phase Florisil 
      columns. The purified POPs were further separated by the capillary columns, and 
      detected by the gas chromatography-electron capture detection (GC-ECD). RESULTS: 
      The average recovery rates of 6 types of organochlorine-based pesticides were 
      80.2%-112.1%, which represent the first 3 categories of the 12 species of POPs. 
      The precise quantities detected were 3.85%-9.32% (the limits of detection were 
      0.03 microg/l to 0.08 microg/l), and the linear correlation coefficients were 
      >or=0.9969. Of the 36 women tested, 10 (27.8%) were found to have colostrums 
      containing traces of dichloro-diphenyl-trichloroethane (DDT), and 2 (5.56%) were 
      tested positive for dieldrin. CONCLUSIONS: The combination of using GC-ECD proved 
      to be both accurate and reliable, and this process proved to be both simple and 
      time-effective. This method is applicable for determining the levels of POPs in 
      organisms.
FAU - Wang, De-Cai
AU  - Wang DC
AD  - Public Health College, Harbin Medical University, Harbin, People's Republic of 
      China.
FAU - Yu, Ping
AU  - Yu P
FAU - Zhang, Yang
AU  - Zhang Y
FAU - Cui, Yu
AU  - Cui Y
FAU - Sun, Chang-Hao
AU  - Sun CH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080712
PL  - Netherlands
TA  - Clin Chim Acta
JT  - Clinica chimica acta; international journal of clinical chemistry
JID - 1302422
RN  - 0 (Environmental Pollutants)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Adult
MH  - Chromatography, Gas/*methods
MH  - Colostrum/*chemistry
MH  - Environmental Pollutants/*analysis/isolation & purification
MH  - Female
MH  - Humans
MH  - Obstetric Labor, Premature
MH  - Pesticide Residues/*analysis/isolation & purification
MH  - Pregnancy
EDAT- 2008/08/13 09:00
MHDA- 2009/04/18 09:00
CRDT- 2008/08/13 09:00
PHST- 2008/03/22 00:00 [received]
PHST- 2008/06/19 00:00 [revised]
PHST- 2008/07/07 00:00 [accepted]
PHST- 2008/08/13 09:00 [pubmed]
PHST- 2009/04/18 09:00 [medline]
PHST- 2008/08/13 09:00 [entrez]
AID - S0009-8981(08)00332-X [pii]
AID - 10.1016/j.cca.2008.07.004 [doi]
PST - ppublish
SO  - Clin Chim Acta. 2008 Nov;397(1-2):18-21. doi: 10.1016/j.cca.2008.07.004. Epub 
      2008 Jul 12.