PMID- 18697232
OWN - NLM
STAT- MEDLINE
DCOM- 20081030
LR  - 20080903
IS  - 0951-4198 (Print)
IS  - 0951-4198 (Linking)
VI  - 22
IP  - 18
DP  - 2008 Sep
TI  - Atmospheric pressure glow discharge desorption mass spectrometry for rapid 
      screening of pesticides in food.
PG  - 2791-8
LID - 10.1002/rcm.3677 [doi]
AB  - Flowing afterglow atmospheric pressure glow discharge tandem mass spectrometry 
      (APGD-MS/MS) is used for the analysis of trace amounts of pesticides in fruit 
      juices and on fruit peel. The APGD source was rebuilt after Andrade et al. 
      (Andrade et al., Anal. Chem. 2008; 80: 2646-2653; 2654-2663) and mounted onto a 
      hybrid quadrupole time-of-flight mass spectrometer. Apple, cranberry, grape and 
      orange juices as well as fruit peel and salad leaves were spiked with aqueous 
      solutions containing trace amounts of the pesticides alachlor, atrazine, 
      carbendazim, carbofuran, dinoseb, isoproturon, metolachlor, metolcarb, propoxur 
      and simazine. Best limits of determination (LODs) of pesticides in the fruit 
      juices were achieved for metolcarb (1 microg/L in apple juice), carbofuran and 
      dinoseb (2 microg/L in apple juice); for the analysis of apple skin best LODs 
      were 10 pg/cm(2) of atrazine, metolcarb and propoxur which corresponds to an 
      estimated concentration of 0.01 microg/kg apple, taking into account the surface 
      area and the weight of the apple. The measured LODs were within or below the 
      allowed maximum residue levels (MRLs) decreed by the European Union (1-500 
      microg/kg for pesticides in fruit juice and 0.01-5 microg/kg for apple skin). No 
      sample pretreatment (extraction, pre-concentration, chromatographic separation) 
      was necessary to analyze these pesticides by direct desorption/ionization using 
      APGD-MS and to identify them using MS/MS. This makes APGD-MS a powerful 
      high-throughput tool for the investigation of very low amounts of pesticides in 
      fruit juices and on fruit peel/vegetable skin.
CI  - Copyright (c) 2008 John Wiley & Sons, Ltd.
FAU - Jecklin, Matthias Conradin
AU  - Jecklin MC
AD  - Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.
FAU - Gamez, Gerardo
AU  - Gamez G
FAU - Touboul, David
AU  - Touboul D
FAU - Zenobi, Renato
AU  - Zenobi R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Rapid Commun Mass Spectrom
JT  - Rapid communications in mass spectrometry : RCM
JID - 8802365
RN  - 0 (Pesticides)
SB  - IM
MH  - Atmospheric Pressure
MH  - Food Analysis/*methods
MH  - Food Contamination/*analysis
MH  - Mass Spectrometry/*methods
MH  - Pesticides/*analysis
EDAT- 2008/08/13 09:00
MHDA- 2008/10/31 09:00
CRDT- 2008/08/13 09:00
PHST- 2008/08/13 09:00 [pubmed]
PHST- 2008/10/31 09:00 [medline]
PHST- 2008/08/13 09:00 [entrez]
AID - 10.1002/rcm.3677 [doi]
PST - ppublish
SO  - Rapid Commun Mass Spectrom. 2008 Sep;22(18):2791-8. doi: 10.1002/rcm.3677.