PMID- 18708686
OWN - NLM
STAT- MEDLINE
DCOM- 20081208
LR  - 20191111
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 18
IP  - 4
DP  - 2008 Aug
TI  - Influence of carbohydrate-protein beverage on cycling endurance and indices of 
      muscle disruption.
PG  - 363-78
AB  - Carbohydrate-protein (CHO+Pro) beverages reportedly improve endurance and indices 
      of muscle disruption, but it is unclear whether these effects are related to 
      total energy intake or specific effects of protein. PURPOSE: The authors examined 
      effects of CHO+Pro on time to exhaustion and markers of muscle disruption 
      compared with placebo (PLA) and carbohydrate beverages matched for carbohydrate 
      (CHO) and total calories (CHO+CHO). METHODS: Eleven male cyclists completed 4 
      rides to exhaustion at 75% VO2peak. Participants consumed 250 ml of PLA, CHO 
      (7.75%), CHO+CHO (9.69%), or CHO+Pro (7.75%/1.94%) every 15 min until fatigue, in 
      a double-blind design. RESULTS: Time to exhaustion was significantly longer 
      (p<.05) in CHO+Pro (126.2+/-25.4 min) and CHO+CHO (121.3+/-36.8) than PLA 
      (107.1+/-30.3). CHO (117.5+/-24.2) and PLA were not significantly different. 
      Similarly, CHO+Pro was not significantly different from CHO and CHO+CHO. 
      Postexercise plasma creatine kinase was lower after CHO+Pro (197.2+/-149.2 IU/L) 
      than PLA (407.4+/-391.3), CHO (373.2+/-416.6), and CHO+CHO (412.3+/-410.2). 
      Postexercise serum myoglobin was lower in CHO+Pro (47.0+/-27.4 ng/mL) than all 
      other treatments (168.8+/-217.3, 82.6+/-71.3, and 72.0+/-75.8). Postexercise leg 
      extensions at 70% 1RM were significantly greater 24 hr after CHO+Pro (11.3+/-4.1) 
      than PLA (8.8+/-3.7), CHO (9.7+/-4.3), and CHO+CHO (9.5+/-3.6). CONCLUSION: These 
      findings suggest that at least some of the reported improvements in endurance 
      with CHO+Pro beverages might be related to caloric differences between 
      treatments. Postexercise improvements in markers of muscle disruption with 
      CHO+Pro ingestion appear to be independent of carbohydrate and caloric content 
      and were elicited with beverages consumed only during exercise.
FAU - Valentine, Rudy J
AU  - Valentine RJ
AD  - Department of Kinesiology, James Madison University, Harrisonburg, VA 22807, USA.
FAU - Saunders, Michael J
AU  - Saunders MJ
FAU - Todd, M Kent
AU  - Todd MK
FAU - St Laurent, Thomas G
AU  - St Laurent TG
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Beverages
MH  - *Bicycling/physiology
MH  - Cross-Over Studies
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Proteins/*administration & dosage
MH  - Double-Blind Method
MH  - Energy Intake/*physiology
MH  - Humans
MH  - Male
MH  - Muscle, Skeletal/injuries/*metabolism
MH  - Oxygen Consumption
MH  - Physical Endurance/*drug effects/physiology
MH  - Time Factors
MH  - Young Adult
EDAT- 2008/08/19 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/08/19 09:00
PHST- 2008/08/19 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/08/19 09:00 [entrez]
AID - 10.1123/ijsnem.18.4.363 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2008 Aug;18(4):363-78. doi: 
      10.1123/ijsnem.18.4.363.