PMID- 18712406 OWN - NLM STAT- MEDLINE DCOM- 20090519 LR - 20211020 IS - 1432-1246 (Electronic) IS - 0340-0131 (Linking) VI - 82 IP - 4 DP - 2009 Mar TI - Levels of metals and organic substances in workers at a hazardous waste incinerator: a follow-up study. PG - 519-28 LID - 10.1007/s00420-008-0350-0 [doi] AB - PURPOSE: To determine the blood and urine concentrations of a number of metals and organic substances in workers at a hazardous waste incinerator (HWI) in Catalonia, Spain, 8 years after regular operations in the facility. To compare these concentrations with the baseline (1999) levels and with those obtained in previous (2000 and 2005) surveys. METHODS: The employees were divided into three groups according to their specific workplaces. Plasma analyses of hexachlorobenzene (HCB), polychlorinated biphenyls (PCBs 28, 52, 101, 138, 153 and 180) and polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), as well as urinary analyses of 2,4- and 2,5-dichlorophenol (DCP), 2,4,5- and 2,4,6-trichlorophenol (TCP), pentachlorophenol (PCP) and 1-hydroxypyrene (1-HP) were carried out. Blood concentrations of manganese and mercury, and urinary levels of nickel were also determined. RESULTS: For organic compounds in plasma, the comparison of the current levels with those of previous surveys did not show any significant increase for any of the compounds analyzed. In contrast, plasma levels of PCBs 28, 52 and 101 were significantly lower than the respective baseline concentrations, while especially notable was the significant reduction in the levels of PCDD/Fs in plasma of plant workers, which decreased from 26.7 pg I-TEQ/g lipid in the baseline survey to the current 2.5 pg I-TEQ/g lipid. CONCLUSION: According to the results of the present study, there are no evident signs of occupational exposure to a number of metals and organic substances in the workers of the HWI. FAU - Mari, Montse AU - Mari M AD - Department of Chemical Engineering, School of Chemical Engineering, Rovira i Virgili University, Sescelades Campus, Tarragona, Spain. FAU - Schuhmacher, Marta AU - Schuhmacher M FAU - Domingo, Jose L AU - Domingo JL LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20080820 PL - Germany TA - Int Arch Occup Environ Health JT - International archives of occupational and environmental health JID - 7512134 RN - 0 (Benzene Derivatives) RN - 0 (Benzofurans) RN - 0 (Chlorophenols) RN - 0 (Environmental Pollutants) RN - 0 (Hazardous Waste) RN - 0 (Heterocyclic Compounds, 1-Ring) RN - 0 (Metals, Heavy) RN - 0 (Polychlorinated Dibenzodioxins) RN - 0 (Pyrenes) RN - 32526637PN (2,4,5-trichlorophenol) RN - 3B11G9AKBA (2,5-dichlorophenol) RN - 4Z87H0LKUY (Hexachlorobenzene) RN - 8U54U639VI (dibenzofuran) RN - D9BSU0SE4T (Pentachlorophenol) RN - DFC2HB4I0K (Polychlorinated Biphenyls) RN - MHS8C5BAUZ (2,4,6-trichlorophenol) RN - N2H6O5V707 (1-hydroxypyrene) RN - R669TG1950 (2,4-dichlorophenol) SB - IM MH - Benzene Derivatives/*blood/*urine MH - Benzofurans/blood MH - Chlorophenols/urine MH - Environmental Monitoring/methods MH - Environmental Pollutants/blood MH - Female MH - Gas Chromatography-Mass Spectrometry MH - Hazardous Waste/*analysis MH - Heterocyclic Compounds, 1-Ring/*blood MH - Hexachlorobenzene/blood MH - Humans MH - *Incineration MH - Male MH - Metals, Heavy/blood MH - Occupational Exposure/*analysis MH - Pentachlorophenol/urine MH - Polychlorinated Biphenyls/blood MH - Polychlorinated Dibenzodioxins/analogs & derivatives/blood MH - Pyrenes/*analysis MH - Spain EDAT- 2008/08/21 09:00 MHDA- 2009/05/20 09:00 CRDT- 2008/08/21 09:00 PHST- 2008/04/25 00:00 [received] PHST- 2008/08/03 00:00 [accepted] PHST- 2008/08/21 09:00 [pubmed] PHST- 2009/05/20 09:00 [medline] PHST- 2008/08/21 09:00 [entrez] AID - 10.1007/s00420-008-0350-0 [doi] PST - ppublish SO - Int Arch Occup Environ Health. 2009 Mar;82(4):519-28. doi: 10.1007/s00420-008-0350-0. Epub 2008 Aug 20.