PMID- 18716955
OWN - NLM
STAT- MEDLINE
DCOM- 20081124
LR  - 20220330
IS  - 1744-5078 (Electronic)
IS  - 0927-3948 (Linking)
VI  - 16
IP  - 4
DP  - 2008 Jul-Aug
TI  - Ophthalmic manifestations of immune reconstitution inflammatory syndrome 
      associated with Cryptococcus neoformans.
PG  - 185-90
LID - 10.1080/09273940802204550 [doi]
AB  - PURPOSE: To describe the ophthalmic manifestations of immune reconstitution 
      inflammatory syndrome (IRIS) associated with Cryptococcus neoformans. METHODS: 
      Four HIV-positive patients on highly active anti-retroviral therapy (HAART) 
      presented with marked optic disk swelling. RESULTS: Three months after the 
      episode of IRIS, 2 of the patients maintained 20/20 visual acuity whose elevated 
      intracranial pressure (ICP) was successfully managed, while 2 patients visual 
      acuities were worse than 20/400 whose ICP was persistently elevated. CONCLUSION: 
      Cryptococcus is another opportunistic infectious organism associated with IRIS 
      with ophthalmic manifestations. Ophthalmologists have the opportunity to play a 
      key role in the early diagnosis and management to prevent serious visual loss.
FAU - Khurana, Rahul N
AU  - Khurana RN
AD  - Uveitis & Ocular Pathology, Dohney Eye Institute, Los Angeles, California 90033, 
      USA.
FAU - Javaheri, Micheal
AU  - Javaheri M
FAU - Rao, Narsing
AU  - Rao N
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Ocul Immunol Inflamm
JT  - Ocular immunology and inflammation
JID - 9312169
RN  - 0 (Antigens, Fungal)
RN  - 0 (Diuretics)
RN  - O3FX965V0I (Acetazolamide)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/diagnosis/drug therapy/*microbiology
MH  - Acetazolamide/therapeutic use
MH  - Adult
MH  - Antigens, Fungal/cerebrospinal fluid
MH  - Antiretroviral Therapy, Highly Active
MH  - CD4 Lymphocyte Count
MH  - Cryptococcosis/diagnosis/drug therapy/*microbiology
MH  - Cryptococcus neoformans/*isolation & purification
MH  - Diuretics/therapeutic use
MH  - Eye Infections, Fungal/diagnosis/drug therapy/*microbiology
MH  - Female
MH  - HIV Seropositivity/complications/drug therapy
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/diagnosis/drug therapy/*microbiology
MH  - Intracranial Hypertension/diagnosis/drug therapy/microbiology
MH  - Male
MH  - Middle Aged
MH  - Papilledema/diagnosis/drug therapy/microbiology
MH  - Retinal Hemorrhage/diagnosis/drug therapy/microbiology
MH  - Retrospective Studies
MH  - Spinal Puncture
MH  - Viral Load
EDAT- 2008/08/22 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/08/22 09:00
PHST- 2008/08/22 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/08/22 09:00 [entrez]
AID - 901776033 [pii]
AID - 10.1080/09273940802204550 [doi]
PST - ppublish
SO  - Ocul Immunol Inflamm. 2008 Jul-Aug;16(4):185-90. doi: 10.1080/09273940802204550.