PMID- 18721010 OWN - NLM STAT- MEDLINE DCOM- 20081230 LR - 20080825 IS - 1092-6429 (Print) IS - 1092-6429 (Linking) VI - 18 IP - 4 DP - 2008 Aug TI - Laparoscopic bilateral simultaneous adrenalectomy: results of 11 operations. PG - 588-92 LID - 10.1089/lap.2007.0116 [doi] AB - BACKGROUND: This study was undertaken to evaluate the outcomes of the simultaneous bilateral laparoscopic adrenalectomy. MATERIALS AND METHODS: This was a retrospective study, including 11 patients with bilateral adrenal lesions, affected by Cushing's syndrome (n=2), Cushing's disease (n=6), pheochromocytoma (n=2), and 1 adrenocorticotrophin-hormone-dependent hypercortisolism of unknown origin. RESULTS: Elevan bilateral adrenalectomies were carried out by the laparoscopic approach with no conversions. The operations were performed in 7 cases by the lateral transperitoneal adrenalectomy (LTLA), in 3 by the posterior approach (PRA), and in 1 by the combined approach. The mean size of the masses was 5 cm. (range, 4-13). The average operating time was 245 minutes for LTLA and 218 minutes for PRA (P<0.05). The estimated mean blood loss was 87+/-36 mL (range, 20-150). No patients required transfusions. The mean hospital stay was 5+/-1.8 days (range, 4-7). The mean follow-up was 34 months (range, 2-96). CONCLUSIONS: Our study confirms that the bilateral adrenalectomy by the minimally invasive technique is safe and effective, affording acceptable blood loss and morbidity with a short hospital stay. FAU - Pugliese, Raffaele AU - Pugliese R AD - Department of Surgery, Niguarda Hospital, Milan, Italy. FAU - Boniardi, Marco AU - Boniardi M FAU - de Carli, Stefano AU - de Carli S FAU - Sansonna, Fabio AU - Sansonna F FAU - Costanzi, Andrea AU - Costanzi A FAU - Maggioni, Dario AU - Maggioni D FAU - Ferrari, Giovanni C AU - Ferrari GC FAU - Di Lernia, Stefano AU - Di Lernia S FAU - Loli, Paola AU - Loli P FAU - Grossrubatscher, Erika AU - Grossrubatscher E LA - eng PT - Journal Article PL - United States TA - J Laparoendosc Adv Surg Tech A JT - Journal of laparoendoscopic & advanced surgical techniques. Part A JID - 9706293 SB - IM MH - Adolescent MH - Adrenal Gland Neoplasms/surgery MH - Adrenalectomy/*methods MH - Adrenocortical Hyperfunction/surgery MH - Adult MH - Blood Loss, Surgical/physiopathology MH - Cushing Syndrome/surgery MH - Female MH - Humans MH - Laparoscopy/*methods MH - Length of Stay MH - Male MH - Middle Aged MH - Pheochromocytoma/surgery MH - Retrospective Studies MH - Treatment Outcome EDAT- 2008/08/30 09:00 MHDA- 2008/12/31 09:00 CRDT- 2008/08/30 09:00 PHST- 2008/08/30 09:00 [pubmed] PHST- 2008/12/31 09:00 [medline] PHST- 2008/08/30 09:00 [entrez] AID - 10.1089/lap.2007.0116 [doi] PST - ppublish SO - J Laparoendosc Adv Surg Tech A. 2008 Aug;18(4):588-92. doi: 10.1089/lap.2007.0116.