PMID- 1872992
OWN - NLM
STAT- MEDLINE
DCOM- 19910926
LR  - 20190912
IS  - 0741-8329 (Print)
IS  - 0741-8329 (Linking)
VI  - 8
IP  - 4
DP  - 1991 Jul-Aug
TI  - Fat-preferring rats consume more alcohol than carbohydrate-preferring rats.
PG  - 313-6
AB  - Rats with a genetic preference for alcohol (ETOH) have been found to consume more 
      dietary fat then ETOH nonpreferring rats. We therefore hypothesized that rats 
      selected on the basis of fat and carbohydrate (CHO) preferences would differ in 
      ETOH intake. Patterns of macronutrient self-selection were determined by allowing 
      rats to select diets from separate sources of CHO, fat and protein. Subsequently, 
      CHO- and fat-preferring groups were formed. All rats were then returned to a lab 
      chow diet and trained to drink ETOH (4-12%) during one hour of access per day. 
      Food restriction was used only in the first three weeks of the procedure. On the 
      final drinking sessions, water and ETOH were alternated on a daily basis. 
      Fat-preferring rats consumed significantly more ETOH than water; CHO-preferring 
      rats consumed approximately equal amounts of ETOH and water. Furthermore, 
      fat-preferring rats consumed more ETOH than CHO-preferring rats. This study 
      suggests that there may be a common mechanism underlying diet preference and oral 
      intake of ETOH.
FAU - Krahn, D D
AU  - Krahn DD
AD  - Eating Disorders Program, University of Michigan Medical Center, Ann Arbor 
      48109-0116.
FAU - Gosnell, B A
AU  - Gosnell BA
LA  - eng
GR  - DA05471/DA/NIDA NIH HHS/United States
GR  - DA06827/DA/NIDA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Alcohol
JT  - Alcohol (Fayetteville, N.Y.)
JID - 8502311
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
SB  - IM
MH  - *Alcohol Drinking
MH  - Animals
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Fats/*administration & dosage
MH  - *Food Preferences
MH  - Male
MH  - Rats
MH  - Rats, Inbred Strains
EDAT- 1991/07/01 00:00
MHDA- 1991/07/01 00:01
CRDT- 1991/07/01 00:00
PHST- 1991/07/01 00:00 [pubmed]
PHST- 1991/07/01 00:01 [medline]
PHST- 1991/07/01 00:00 [entrez]
AID - 0741-8329(91)90465-9 [pii]
AID - 10.1016/0741-8329(91)90465-9 [doi]
PST - ppublish
SO  - Alcohol. 1991 Jul-Aug;8(4):313-6. doi: 10.1016/0741-8329(91)90465-9.