PMID- 18760164
OWN - NLM
STAT- MEDLINE
DCOM- 20080923
LR  - 20220318
IS  - 1532-821X (Electronic)
IS  - 0003-9993 (Linking)
VI  - 89
IP  - 9
DP  - 2008 Sep
TI  - Estimating maximum work rate during incremental cycle ergometry testing from 
      six-minute walk distance in patients with chronic obstructive pulmonary disease.
PG  - 1782-7
LID - 10.1016/j.apmr.2008.01.020 [doi]
AB  - OBJECTIVE: To develop a predictive equation to permit estimation of the maximum 
      work rate (Wmax) achieved during an incremental cycle ergometry test from the 
      measurement of 6-minute walk distance (6MWD) and its derivative, 6-minute walk 
      work, which is the product of 6MWD and body weight. DESIGN: Cross-sectional 
      observational study. SETTING: Outpatient physiotherapy and pulmonary physiology 
      clinics in a tertiary hospital. PARTICIPANTS: Patients (N=50; 36 men) with 
      chronic obstructive pulmonary disease (forced expiratory volume in 1 second 
      [FEV(1)]=37%+/-11% of predicted). INTERVENTIONS: Not applicable. MAIN OUTCOME 
      MEASURES: Measurements were obtained of 6MWD and Wmax achieved during a 
      laboratory-based, symptom-limited incremental cycle ergometry test. Linear 
      regression analyses were performed using 6MWD, height, weight, and FEV(1) and 
      using 6-minute walk work, height, and FEV(1) to determine their contribution to 
      Wmax and to develop predictive equations for estimating Wmax. RESULTS: The 
      equations derived to estimate Wmax using 6MWD and 6-minute walk work, 
      respectively, were as follows: Wmax (W)=(0.122 x 6MWD)+(72.683 x height 
      [m])-117.109 (r(2)=.67, standard error of the estimate [SEE]=10.8W) and Wmax 
      (W)=17.393+(1.442 x 6-minute walk work) (r(2)=.60, SEE=11.8W). CONCLUSIONS: Wmax 
      can be estimated from equations based on measurements of 6MWD or 6-minute walk 
      work. The estimate of Wmax derived from either equation may provide a basis on 
      which to prescribe cycle ergometry training work rates that comply with the 
      current guidelines for pulmonary rehabilitation.
FAU - Hill, Kylie
AU  - Hill K
AD  - Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, 
      Western Australia, Australia. Kylie.Hill@westpark.org
FAU - Jenkins, Sue C
AU  - Jenkins SC
FAU - Cecins, Nola
AU  - Cecins N
FAU - Philippe, Danielle L
AU  - Philippe DL
FAU - Hillman, David R
AU  - Hillman DR
FAU - Eastwood, Peter R
AU  - Eastwood PR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arch Phys Med Rehabil
JT  - Archives of physical medicine and rehabilitation
JID - 2985158R
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Analysis of Variance
MH  - Cross-Sectional Studies
MH  - Ergometry
MH  - *Exercise Test
MH  - Female
MH  - Forced Expiratory Volume/physiology
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Oximetry
MH  - Oxygen Consumption/physiology
MH  - Prospective Studies
MH  - Pulmonary Disease, Chronic Obstructive/*physiopathology
MH  - Walking/*physiology
EDAT- 2008/09/02 09:00
MHDA- 2008/09/24 09:00
CRDT- 2008/09/02 09:00
PHST- 2007/12/22 00:00 [received]
PHST- 2008/01/05 00:00 [revised]
PHST- 2008/01/18 00:00 [accepted]
PHST- 2008/09/02 09:00 [pubmed]
PHST- 2008/09/24 09:00 [medline]
PHST- 2008/09/02 09:00 [entrez]
AID - S0003-9993(08)00391-2 [pii]
AID - 10.1016/j.apmr.2008.01.020 [doi]
PST - ppublish
SO  - Arch Phys Med Rehabil. 2008 Sep;89(9):1782-7. doi: 10.1016/j.apmr.2008.01.020.