PMID- 18761421
OWN - NLM
STAT- MEDLINE
DCOM- 20090813
LR  - 20090216
IS  - 1878-5875 (Electronic)
IS  - 1357-2725 (Linking)
VI  - 41
IP  - 5
DP  - 2009 May
TI  - Monocyte chemoattractant protein-1: a key mediator in inflammatory processes.
PG  - 998-1001
LID - 10.1016/j.biocel.2008.07.018 [doi]
AB  - Monocyte chemoattractant protein-1 (MCP-1) is a potent chemoattractant for 
      monocytes and macrophages to areas of inflammation. MCP-1 is a prototypical 
      chemokine subject to coordinated regulation by immunomodulatory agents. Since 
      MCP-1 is implicated in multiple inflammatory diseases, it is a potential target 
      for the treatment of these disorders. In this review, we will provide background 
      information and summarize the MCP-1 structure and signaling pathways. Its 
      involvement in multiple diseases, such as tumour development, atherogenesis and 
      rare autoimmune diseases is also revised.
FAU - Melgarejo, Esther
AU  - Melgarejo E
AD  - Departamento de Biologia Molecular y Bioquimica, Facultad de Ciencias, 
      Universidad de Malaga, E-29071 Malaga, Spain. emelgarejo@uma.es
FAU - Medina, Miguel Angel
AU  - Medina MA
FAU - Sanchez-Jimenez, Francisca
AU  - Sanchez-Jimenez F
FAU - Urdiales, Jose Luis
AU  - Urdiales JL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20080808
PL  - Netherlands
TA  - Int J Biochem Cell Biol
JT  - The international journal of biochemistry & cell biology
JID - 9508482
RN  - 0 (Chemokine CCL2)
SB  - IM
MH  - Animals
MH  - Chemokine CCL2/chemistry/genetics/*immunology
MH  - Humans
MH  - Inflammation/immunology
RF  - 1
EDAT- 2008/09/02 09:00
MHDA- 2009/08/14 09:00
CRDT- 2008/09/02 09:00
PHST- 2008/06/17 00:00 [received]
PHST- 2008/07/14 00:00 [revised]
PHST- 2008/07/17 00:00 [accepted]
PHST- 2008/09/02 09:00 [pubmed]
PHST- 2009/08/14 09:00 [medline]
PHST- 2008/09/02 09:00 [entrez]
AID - S1357-2725(08)00310-5 [pii]
AID - 10.1016/j.biocel.2008.07.018 [doi]
PST - ppublish
SO  - Int J Biochem Cell Biol. 2009 May;41(5):998-1001. doi: 
      10.1016/j.biocel.2008.07.018. Epub 2008 Aug 8.