PMID- 18768303
OWN - NLM
STAT- MEDLINE
DCOM- 20081125
LR  - 20091016
IS  - 0927-7765 (Print)
IS  - 0927-7765 (Linking)
VI  - 66
IP  - 2
DP  - 2008 Oct 15
TI  - Preparation of polyurea capsules using electrocapillary emulsification.
PG  - 287-90
LID - 10.1016/j.colsurfb.2008.07.009 [doi]
AB  - Polyurea capsules have been prepared using the electrocapillary emulsification 
      method in order to control the particle size within the submicron range. The 
      polyurea capsules have been synthesized via the interfacial polycondensation 
      between tetraethylenepentamine (TEP) dissolved in an aqueous phase and 
      toluenediisocyanate (TDI) dissolved in a mixture of cyclohexane and chloroform. 
      The oil phase contains a lipophilic nonionic surfactant (sorbitan sesquioleate, 
      SO-15) as an emulsion stabilizer. Scanning electron microscope (SEM) observations 
      reveal that the capsule size is decreased as (i) the amount of the aqueous phase 
      injected into the oil phase is decreased and (ii) the dropping rate of the 
      aqueous phase is decreased. Indeed, the mole ratio of the two monomers makes a 
      significant impact on the capsule size. Under the best experimental condition 
      examined in this study, we obtained polyurea capsules with a diameter of 
      approximately 200nm, which should be useful in developing bioreactors or 
      carriers.
FAU - Sakai, Hideki
AU  - Sakai H
AD  - Department of Pure and Applied Chemistry, Faculty of Science and Technology, 
      Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, Japan.
FAU - Tanaka, Keisuke
AU  - Tanaka K
FAU - Fukushima, Hiroshi
AU  - Fukushima H
FAU - Tsuchiya, Koji
AU  - Tsuchiya K
FAU - Sakai, Kenichi
AU  - Sakai K
FAU - Kondo, Tamotsu
AU  - Kondo T
FAU - Abe, Masahiko
AU  - Abe M
LA  - eng
PT  - Journal Article
DEP - 20080805
PL  - Netherlands
TA  - Colloids Surf B Biointerfaces
JT  - Colloids and surfaces. B, Biointerfaces
JID - 9315133
RN  - 0 (Capsules)
RN  - 0 (Drug Carriers)
RN  - 0 (Emulsions)
RN  - 0 (Polymers)
RN  - 37955-36-5 (polyurea)
SB  - IM
MH  - Capsules
MH  - Drug Carriers/chemical synthesis/chemistry
MH  - Electrochemistry
MH  - Emulsions
MH  - Molecular Structure
MH  - Particle Size
MH  - Polymers/*chemical synthesis/chemistry
MH  - Surface Properties
EDAT- 2008/09/05 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/09/05 09:00
PHST- 2008/04/27 00:00 [received]
PHST- 2008/07/12 00:00 [revised]
PHST- 2008/07/20 00:00 [accepted]
PHST- 2008/09/05 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/09/05 09:00 [entrez]
AID - S0927-7765(08)00273-7 [pii]
AID - 10.1016/j.colsurfb.2008.07.009 [doi]
PST - ppublish
SO  - Colloids Surf B Biointerfaces. 2008 Oct 15;66(2):287-90. doi: 
      10.1016/j.colsurfb.2008.07.009. Epub 2008 Aug 5.