PMID- 18769848
OWN - NLM
STAT- MEDLINE
DCOM- 20090513
LR  - 20151119
IS  - 1432-0703 (Electronic)
IS  - 0090-4341 (Linking)
VI  - 56
IP  - 3
DP  - 2009 Apr
TI  - Diseases of the Chilean flounder, Paralichthys adspersus (Steindachner, 1867), as 
      a biomarker of marine coastal pollution near the Itata River (Chile): Part II. 
      Histopathological lesions.
PG  - 546-56
LID - 10.1007/s00244-008-9223-5 [doi]
AB  - This study evaluated the histopathological lesions of the Chilean flounder, 
      Paralichthys adspersus, inhabiting the marine coastal area influenced by the 
      Itata River (central Chile) in order to provide an environmental baseline given 
      the plans to discharge effluents from a cellulose plant through a submarine pipe 
      in the area. Flounder were also sampled at two reference sites over the course of 
      1 year. Pathological examinations and descriptions of histopathological lesions 
      follow the ICES suggested protocol: internal and histopathological lesions, 
      condition factor, and hepatosomatic and spleen indexes. The prevalence of fish 
      with histopathological lesions differed significantly among sites. The flounder 
      sampled in the Itata area were the most affected. Evaluation of histopathological 
      lesions observed on the flounder caught in the Itata area revealed (i) 16 
      different types of histopathological lesions, (ii) a high prevalence of lesions 
      in gills and epidermal and hepatic tissue, and (iii) a normal K factor and 
      hepatosomatic index. Significant differences were found in epidermal hyperplasia 
      (EH), chronic dermatitis, telangiectasis (TEL), localized edema in the base of 
      lamellae (LE), fusion of secondary lamellae (FSL), foci of cellular alteration 
      (FCA), melanomacrophagic centers (MMCs), and hemosiderin (HEM) lesions among 
      sites and among sites by season of the year. Winter 2006 was the most affected. A 
      seasonal analysis of histopathological lesions on flounder caught in the Itata 
      area showed significant differences for EH, progressive focal invasion of muscle 
      fibers (PFIMF), TEL, LE, FSL, lamellar bifurcation, hepatitis, FCA, MMCs, and HEM 
      lesions between the sampled seasons of the year; flounder caught in winter 2006 
      had the highest prevalence of these lesions except for PFIMF, which was higher in 
      winter 2007. These results are discussed in relation to the contents of inorganic 
      and organic compounds in the water column and the contents of organic compounds 
      in sediments of the subtidal environment in the Itata area.
FAU - Leonardi, Maritza
AU  - Leonardi M
AD  - PIMEX-ARAUCO Program, Faculty of Natural Sciences and Oceanography, University of 
      Concepcion, Concepcion, Chile, mleonard@udec.cl.
FAU - Tarifeno, Eduardo
AU  - Tarifeno E
FAU - Vera, Jeanett
AU  - Vera J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080904
PL  - United States
TA  - Arch Environ Contam Toxicol
JT  - Archives of environmental contamination and toxicology
JID - 0357245
RN  - 0 (Biomarkers)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - Biomarkers
MH  - *Environmental Monitoring
MH  - Fish Diseases/chemically induced/*pathology
MH  - *Flounder
MH  - Rivers/*chemistry
MH  - Seasons
MH  - Skin/pathology
MH  - Water Pollutants, Chemical/*analysis/toxicity
EDAT- 2008/09/05 09:00
MHDA- 2009/05/14 09:00
CRDT- 2008/09/05 09:00
PHST- 2008/04/15 00:00 [received]
PHST- 2008/08/11 00:00 [accepted]
PHST- 2008/09/05 09:00 [pubmed]
PHST- 2009/05/14 09:00 [medline]
PHST- 2008/09/05 09:00 [entrez]
AID - 10.1007/s00244-008-9223-5 [doi]
PST - ppublish
SO  - Arch Environ Contam Toxicol. 2009 Apr;56(3):546-56. doi: 
      10.1007/s00244-008-9223-5. Epub 2008 Sep 4.